VANISH Trial
Does early vasopressin use reduce the risk of kidney failure in patients with septic shock compared with norepinephrine?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
Does early vasopressin use reduce the risk of kidney failure in patients with septic shock compared with norepinephrine?
Continue reading »In adult ICU patients with severe sepsis does the use of continuous infusion (CI) of beta-lactam antibiotics compared to intermittent bolus (IB) improve clinical outcomes?
Continue reading »In paediatric patients with septic shock, does adrenaline compared with dopamine reduce 28 day mortality?
Continue reading »In patients with intraabdominal sepsis and who have received adequate source control, does a fixed short course of antibiotics result in similar treatment success compared to a longer duration of antibiotic therapy?
Continue reading »In paediatric patients with severe febrile illnesses, in a resource limited setting, do fluid boluses with albumin vs. saline vs. no fluid boluses affect mortality?
Continue reading »In patients with septic shock, what is the relationship between appropriateness of initial empiric antimicrobial therapy and survival?
Continue reading »In adult patients with septic shock, does early goal-directed therapy (EGDT) compared with standard therapy reduce mortality at 90 days?
Continue reading »In patients with acute kidney injury (AKI) and severe sepsis or septic shock, does extended daily haemofiltration (EDHF) compared with continuous venovenous haemofiltration (CVVHF) reduce time to renal recovery or mortality at 60 days?
Continue reading »Does the use of the short-acting β-blocker esmolol effectively control heart rate (HR) in patients with septic shock?
Continue reading »In patients with septic shock, does Activated Protein C (also known as drotrecogin alfa or DrotAA) compared with placebo reduce mortality?
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