TRACT Tranfusion Timing
In children hospitalised with uncomplicated severe anaemia, is an immediate blood transfusion strategy superior to delayed transfusion in reducing 28-day mortality?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
In children hospitalised with uncomplicated severe anaemia, is an immediate blood transfusion strategy superior to delayed transfusion in reducing 28-day mortality?
Continue reading »In patients undergoing cardiac surgery, who have a moderate-to-high risk of death, does a restrictive transfusion strategy compared with a liberal strategy impact on a composite outcome of death, myocardial infarction, stroke and acute kidney injury requiring dialysis at 6 months after surgery?
Continue reading »In severely injured patients at risk for haemorrhagic shock, does prehospital plasma resuscitation, compared with standard-care resuscitation (not including plasma administration), reduce 30-day mortality?
Continue reading »In patients undergoing cardiac surgery, who have a moderate-to-high risk of death, does a restrictive transfusion strategy compared with a liberal strategy impact on a composite outcome of death, myocardial infarction, stroke and acute kidney injury requiring dialysis
Continue reading »In critically ill patients requiring transfusion, does the transfusion of the freshest available red cells compared to standard care impact on patient mortality?
Continue reading »In cancer patients with septic shock does a restrictive vs. a liberal transfusion threshold reduce 28 day mortality?
Continue reading »In critically ill patients who are anaemic, does early administration of intravenous iron compared to placebo reduce the requirement for blood transfusion?
Continue reading »In critically ill patients requiring blood, does transfusion with “fresh” RBC’s (stored for 8 days or less) compared with standard issue RBCs (stored 2-42 days) reduce 90 day mortality?
Continue reading »In adults undergoing cardiac surgery, does a restrictive transfusion strategy (Hb > 75 g/l) compared to a liberal transfusion strategy (Hb > 90 g/l) lead to fewer infections and ischaemic events within 3 months?
Continue reading »In trauma patients with or at risk of significant haemorrhage, does the early administration of a short course of tranexamic acid (TXA) affect the mortality, incidence of occlusive events and the amount of blood transfused?
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