Search Results for “PILOT”

PILOT

2 December 2022 Omar Jundi Intensive Care Medicine 2 comments

Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation Semler. N Engl J Med 2022; 387:1759-1769. DOI: 10.1056/NEJMoa2208415 Clinical Question In patients receiving invasive mechanical ventilation, does a target oxygen saturation of 90%, 94%, or 98% increase days alive and free of mechanical ventilation at 28 days? Background Despite the ubiquity of oxygen therapy in the critical care setting, the […]

Critical Care Evidence Updates – February 2026

13 March 2026 Rebecca Howes Blog, Evidence-based Medicine Leave a comment

What’s new in the Critical Care literature – monthly updates

Critical Care Evidence Updates – January 2026

19 February 2026 Rebecca Howes Evidence-based Medicine Leave a comment

What’s new in the Critical Care literature – monthly updates

Emergency Evidence Updates – January 2026

19 February 2026 Rebecca Howes Blog, Evidence-based Medicine Leave a comment

What’s new in the Critical Care literature – monthly updates

Delirium Reduction via Scripted Family Voice Recordings in Critically Ill Patients Receiving Mechanical Ventilation

28 January 2026 Mark Giza Intensive Care Medicine, Summaries Leave a comment

Delirium Reduction via Scripted Family Voice Recordings in Critically Ill Patients Receiving Mechanical Ventilation CL Munro. Am J Crit Care. 2025; Nov 1;34(6):429-437. doi: 10.4037/ajcc2025486 Clinical Question In mechanically ventilated adult ICU patients, does a structured voice reorientation intervention recorded by family members, compared to usual care, reduce delirium? Background Delirium affects a significant proportion of patients receiving mechanical ventilation. […]

CLIPII – Cryopreserved vs Liquid-Stored Platelets

13 January 2026 Generic Contributor Intensive Care Medicine, Peri-operative Medicine Leave a comment

Cryopreserved vs Liquid-Stored Platelets for the Treatment of Surgical Bleeding: The CLIP-II Randomized Noninferiority Clinical Trial Reade. JAMA, 2025. doi: 10.1001/jama.2025.23355 Clinical Question In adult cardiac surgery patients at high risk of bleeding, is the transfusion of cryopreserved platelets, compared with conventional liquid-stored platelets, non-inferior in reducing postoperative bleeding within the first 24 hours after ICU admission? Background Platelet transfusion […]