Tag: acute kidney injury

LIBERATE-D – Conservative Dialysis Strategy

1 May 2026 Samuel Brockbank Intensive Care Medicine, Summaries Leave a comment

LIBERATE-D – A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury: The Liberation From Acute Dialysis (LIBERATE-D) Randomized Clinical Trial Liu KD, Siew ED, Tuot DS, Vijayan A, Umemoto GM, Birkelo BC, et al. JAMA. 2026;335(4):326–335. doi:10.1001/jama.2025.21530 Clinical Question In clinically stable adults with AKI-D receiving IHD and expected to require outpatient dialysis after discharge, does […]

BigPAK-2 – preventive care strategy to reduce acute kidney injury after major surgery

A preventive care strategy to reduce moderate or severe acute kidney injury after major surgery (BigpAK-2); a multinational, randomised clinical trial Zarbock. The Lancet 2025. doi: 10.1016/S0140-6736(25)01717-9 Clinical Question In patients at high risk of AKI undergoing major surgery, does a preventative care strategy based on KDIGO guidelines, compared to standard care lead to a reduction in moderate/severe AKI within […]