Category: Peri-operative Medicine

A collection of TBL summaries relevant to Peri-operative Medicine

PALACS

Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery Mario Gaudino, The Lancet Dec 4 2021; 398: 2075–83 https://doi.org/10.1016/S0140-6736(21)02490-9 Clinical Question In selected patients undergoing cardiac surgery, does posterior left pericardiotomy compared with usual care, reduce the incidence of postoperative atrial fibrillation? Background Atrial fibrillation is common following cardiac surgery with approximately one-third of patients developing […]

CONTROLING

Individualised versus conventional glucose control in critically-ill patients: the CONTROLING study—a randomized clinical trial Bohé. Intensive Care Medicine 2021. https://doi.org/10.1007/s00134-021-06526-8 Clinical Question In critically unwell adults does targeting individualised glycaemic control compared to glycaemia < 180 mg/dL improve 90 day mortality? Background Hyperglycaemia has been shown to result in worse outcomes in the critically ill, especially in non-diabetic patients In […]

TRAAP2

14 May 2021 George Walker Peri-operative Medicine Leave a comment

In patients undergoing caesarean section (CS) does the administration of tranexamic acid (TXA) when compared to placebo result in a lower incidence of calculated estimated blood loss of red blood cell transfusion by day 2?

Sjöblom

29 April 2021 Fraser Magee Emergency Medicine, Intensive Care Medicine, Peri-operative Medicine Leave a comment

In adult patients undergoing rapid sequence intubation for emergency surgery, does pre-oxygenation with high-flow nasal oxygen, compared with standard face-mask oxygen, reduce the incidence of oxygen desaturation?

Dex-CSDH

26 January 2021 Celia Bradford Intensive Care Medicine, Peri-operative Medicine Leave a comment

In patients with chronic subdural haemorrhage, what effect does dexamethasone compared with placebo have on neurological outcome at 6 months?

CURASMUR

29 February 2020 Fraser Magee Emergency Medicine, Intensive Care Medicine, Peri-operative Medicine One comment

In patients requiring emergency out-of-hospital endotracheal intubation, is rocuronium non-inferior to suxamethonium in providing a successful first pass attempt?

Sessler

29 November 2019 Segun Olusanya Peri-operative Medicine Leave a comment

In patients with breast cancer having potentially curative surgery, does a strategy of paravertebral block and propofol anaesthesia, compared to a strategy of opioid and sevoflurane anaesthesia, reduce local or metastatic recurrence?

BALANCE

15 November 2019 Duncan Chambler Peri-operative Medicine Leave a comment

In patients undergoing major surgery who are at high risk of complications, does light anaesthesia (BIS 50) compared with deep anaesthesia (BIS 35) improve survival at 1-year?

PAUSE

13 September 2019 Celia Bradford Intensive Care Medicine, Peri-operative Medicine Leave a comment

In patients with atrial fibrillation (AF) on direct oral anticoagulant (DOAC) medications, does a standard approach to therapy interruption and resumption in the perioperative period result in an acceptable risk for bleeding and thromboembolic events?

Zochios

30 August 2019 Peter Szedlak Intensive Care Medicine, Peri-operative Medicine Leave a comment

In patients at high risk of respiratory complications after cardiac surgery, does the routine application of high-flow nasal oxygen compared to standard oxygen reduce hospital length of stay?

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