A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A collection of TBL summaries relevant to Peri-operative Medicine
In patients with atrial fibrillation (AF) on direct oral anticoagulant (DOAC) medications, does a standard approach to therapy interruption and resumption in the perioperative period result in an acceptable risk for bleeding and thromboembolic events?
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In patients at high risk of respiratory complications after cardiac surgery, does the routine application of high-flow nasal oxygen compared to standard oxygen reduce hospital length of stay?
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In obese patients, does the use of recruitment maneuvers with high PEEP, compared with low PEEP, decrease postoperative pulmonary complications?
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Does titrating positive end-expiratory pressure (PEEP) with the use of an esophageal balloon to estimate pleural pressure improve outcomes compared with an empirical high PEEP –FiO2 strategy in patients with moderate – severe acute respiratory distress syndrome (ARDS)
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In adult ICU patients undergoing tracheal intubation, does bag mask ventilation (BMV) between induction and laryngoscopy reduce the risk of hypoxaemia?
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In high-risk patients undergoing major abdominal surgery, does epidural analgesia compared with no epidural analgesia reduce mortality and morbidity?
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In adult critically ill patients receiving pharmacological thromboprophylaxis, does the use of adjunctive intermittent pneumatic compression devices result in a lower incidence of proximal deep vein thrombosis (DVT)?
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In adult patients undergoing abdominal surgery, with intermediate-to-high-risk of post-operative pulmonary complications, will an individualised perioperative open-lung ventilation strategy (iPROVE), compared with standard protective ventilation, result in fewer post-operative complications during the first 7 days post surgery
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In adult subjects who ingest a small toy part, compared to historical controls of children who have ingested coins, is there a difference in object transit time and complication rate?
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In mechanically ventilated patients without acute respiratory distress syndrome (ARDS), does a low tidal volume ventilation strategy (6mL/Kg), compared to intermediate tidal volume strategy (10mL/Kg), reduce the number of ventilator-free and alive days at day 28?
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