A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A collection of TBL summaries relevant to Emergency Medicine
In adult patients who have sustained an out of hospital arrhythmia-associated cardiac arrest without an ST-elevation myocardial infarction, is immediate angiography superior to delayed angiography in improving 90-day survival?
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Can extracorporeal carbon dioxide removal (ECCO2R) safely facilitate ultra-low tidal volume ventilation in patients with moderate acute respiratory distress syndrome (ARDS)?
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In adult patients with early septic shock, does peripheral perfusion-targeted resuscitation, compared to lactate level-targeted resuscitation, improve all cause mortality at 28 days?
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In adults with acute, spontaneous intra-cerebral haemorrhage (ICH), does the administration of tranexamic acid (TXA) compared to a placebo improve functional status at 90 days?
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In patients with septic shock, does early low-dose norepinephrine compared with standard care increase shock control at six hours?
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In patients who presented to the Emergency Department (ED) with acute dyspnoea, does the addition of lung ultrasound examination compared to standard approach, improve the diagnostic accuracy for acute decompensated heart failure (ADHF)?
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In patients undergoing rapid sequence anaesthesia induction, does the use of cricoid pressure vs. a sham procedure, prevent pulmonary aspiration?
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Do one or more doses of levocarnitine reduce organ failure in septic shock at 48 hours, compared with placebo?
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In adult subjects who ingest a small toy part, compared to historical controls of children who have ingested coins, is there a difference in object transit time and complication rate?
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In mechanically ventilated patients without acute respiratory distress syndrome (ARDS), does a low tidal volume ventilation strategy (6mL/Kg), compared to intermediate tidal volume strategy (10mL/Kg), reduce the number of ventilator-free and alive days at day 28?
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