Category: Emergency Medicine

A collection of TBL summaries relevant to Emergency Medicine

SCARLET

In adult patients with sepsis-associated coagulopathy does the administration of human recombinant thrombomodulin (rhsTM) compared to placebo reduce 28 day mortality?

EXTEND

31 May 2019 David Slessor Emergency Medicine, Summaries Leave a comment

In patients with acute ischaemic stroke, with salvageable brain tissue, does alteplase compared with placebo, administered between 4.5 – 9 hours post stroke onset, improve functional outcome at 90 days?

PreVent

17 May 2019 Daniel Lane Emergency Medicine, Intensive Care Medicine, Peri-operative Medicine One comment

In adult ICU patients undergoing tracheal intubation, does bag mask ventilation (BMV) between induction and laryngoscopy reduce the risk of hypoxaemia?

SHoC-ED 3

3 May 2019 Adrian Wong Emergency Medicine, Intensive Care Medicine 2 comments

In patients presenting to the Emergency Department (ED) in cardiac arrest, does a standardised point-of-care ultrasound protocol, compared with usual care, affect the length of resuscitation, frequency of interventions, and clinical outcomes?

Woolum

26 April 2019 Jose Chacko Emergency Medicine, Intensive Care Medicine 3 comments

In patients with septic shock, does the administration of thiamine lead to more rapid lactate clearance and improved clinical outcomes?

COACT

5 April 2019 Fraser Magee Emergency Medicine, Intensive Care Medicine Leave a comment

In adult patients who have sustained an out of hospital arrhythmia-associated cardiac arrest without an ST-elevation myocardial infarction, is immediate angiography superior to delayed angiography in improving 90-day survival?

SUPERNOVA

22 March 2019 James Walter Emergency Medicine, Intensive Care Medicine Leave a comment

Can extracorporeal carbon dioxide removal (ECCO2R) safely facilitate ultra-low tidal volume ventilation in patients with moderate acute respiratory distress syndrome (ARDS)?

ANDROMEDA-SHOCK

15 March 2019 Aidan Burrell Emergency Medicine, Intensive Care Medicine 6 comments

In adult patients with early septic shock, does peripheral perfusion-targeted resuscitation, compared to lactate level-targeted resuscitation, improve all cause mortality at 28 days?

TICH-2

8 March 2019 George Walker Emergency Medicine, Intensive Care Medicine Leave a comment

In adults with acute, spontaneous intra-cerebral haemorrhage (ICH), does the administration of tranexamic acid (TXA) compared to a placebo improve functional status at 90 days?