A compendium of critical appraisals in Intensive Care Medicine research and related specialties
In patient with out-of-hospital cardiac arrest, how does the MIRACLE2 score compare with previously reporting scoring systems, for predicting poor neurological outcome at hospital discharge?
Continue reading »
In patients with aneurysmal subarachnoid haemorrhage (aSAH), does lumbar CSF drainage compared to standard therapy improve clinical outcomes as measured by the modified Rankin Scale (mRS) score at 6 months?
Continue reading »
In acutely ill adults (ED / ICU) does the administration of cefipime or piperacillin-tazobactam (pip-taz) result in an increased incidence of AKI or death by day 14?
Continue reading »
What’s new in the Critical Care literature – monthly updates
Continue reading »
What’s new in the Critical Care literature – monthly updates
Continue reading »
Landiolol and Organ Failure in Patients With Septic Shock Whitehouse. JAMA Published online October 25, 2023. doi:10.1001/jama.2023.20134 Clinical Question In patients with tachycardia and septic shock who are treated with high dose norepinephrine does the use of β-blockade for up to 14 days reduce organ failure compared to standard care? Background Many view the use of β-blockade as contentious in […]
Continue reading »
In trauma patients with exsanguinating haemorrhage, does the use of the REBOA (resuscitative endovascular balloon occlusion of the aorta) device with standard care in the emergency department, compared with standard care alone, impact 90-day-mortality?
Continue reading »
What’s new in the Critical Care literature – monthly updates
Continue reading »
What’s new in the Critical Care literature – monthly updates
Continue reading »
In patients with trauma and critical bleeding who require activation of a major haemorrhage protocol, does the empiric administration of 3 pools of cryoprecipitate (6g fibrinogen) within 90 minutes of randomisation (and no more than 3 hours after injury) improve survival, compared to standard care?
Continue reading »