Tag: Ventilation

RENOVATE – High-Flow vs NIV

High-Flow Nasal Oxygen vs Noninvasive Ventilation in Patients with Acute Respiratory Failure RENOVATE and BRICNet Authors. JAMA 2024. doi: 10.1001/jama.2024.26244 Clinical Question In adult patients with acute respiratory failure does the use of high-flow nasal oxygen compared to noninvasive ventilation reduce the rate of endotracheal intubation or death at 7 days? Background Both high-flow nasal oxygen (HFNO) and noninvasive ventilation […]

PREOXI Trial – Noninvasive Ventilation for Preoxygenation

In critically ill patients undergoing tracheal intubation does pre-oxygenation with non-invasive ventilation compared with pre-oxygenation with an oxygen mask reduce the incidence of hypoxemia during intubation?

TAME

19 June 2023 George Walker Evidence-based Medicine, Intensive Care Medicine Leave a comment

In patients resuscitated from out-of-hospital cardiac arrest (OOHCA) does targeted mild hypercapnia compared to targeted normocapnia improve 6-month neurological outcomes?

The REST Trial

13 September 2021 Aidan Burrell Intensive Care Medicine One comment

In mechanically ventilated patients with acute hypoxaemic respiratory failure, does lowering tidal volume using extracorporeal carbon dioxide removal, compared with conventional low tidal volume ventilation, improve day 90 all-cause mortality?

RECOVERY-RS

22 August 2021 Celia Bradford Intensive Care Medicine 5 comments

In hospitalised patients with COVID-19 requiring >40% FiO2 to achieve SaO2>94%, does the use of continuous positive airway pressure (CPAP) or high flow nasal oxygen (HFNO) compared with conventional O2 therapy (COT) reduce the incidence of tracheal intubation or death within 30 days?

HOT-ICU

25 February 2021 Luke Collett Intensive Care Medicine Leave a comment

In patients with acute hypoxaemic respiratory failure, does a lower vs higher oxygenation target reduce mortality at 90 days?

LOCO2

4 September 2020 Luke Collett Intensive Care Medicine, Summaries Leave a comment

In patients with acute respiratory distress syndrome (ARDS), does conservative vs. liberal oxygen reduce death at 28 days?

ICU-ROX

1 November 2019 Celia Bradford Intensive Care Medicine 2 comments

In mechanically ventilated ICU patients does a conservative use of oxygen therapy compared to usual oxygen therapy affect the number of ventilator-free-days?

Subira

20 October 2019 Duncan Chambler Intensive Care Medicine Leave a comment

In patients weaning from mechanical ventilation, does a spontaneous breathing trial (SBT) with pressure support (PS) for 30 minutes vs a SBT with T-piece for 2 hours differ in the rate of successful liberation from mechanical ventilation (MV)?

PHARLAP

20 September 2019 James Walter Intensive Care Medicine Leave a comment

Does an open lung ventilation strategy which includes maximal recruitment maneuvers (RMs) and positive end-expiratory pressure (PEEP) titration improve outcomes compared to traditional lung-protective ventilation in patients with moderate – severe acute respiratory distress syndrome (ARDS)?

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