Category: Summaries

A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.

SCARLET

In adult patients with sepsis-associated coagulopathy does the administration of human recombinant thrombomodulin (rhsTM) compared to placebo reduce 28 day mortality?

EPVent2

Does titrating positive end-expiratory pressure (PEEP) with the use of an esophageal balloon to estimate pleural pressure improve outcomes compared with an empirical high PEEP –FiO2 strategy in patients with moderate – severe acute respiratory distress syndrome (ARDS)

EXTEND

31 May 2019 David Slessor Emergency Medicine, Summaries Leave a comment

In patients with acute ischaemic stroke, with salvageable brain tissue, does alteplase compared with placebo, administered between 4.5 – 9 hours post stroke onset, improve functional outcome at 90 days?

SPICE III

24 May 2019 Celia Bradford Intensive Care Medicine Leave a comment

In ventilated, critically ill patients, does the use of dexmedetomidine as the primary sedative agent compared with usual sedative agents effect 90 day mortality?

PreVent

17 May 2019 Daniel Lane Emergency Medicine, Intensive Care Medicine, Peri-operative Medicine One comment

In adult ICU patients undergoing tracheal intubation, does bag mask ventilation (BMV) between induction and laryngoscopy reduce the risk of hypoxaemia?

MAPAS

11 May 2019 Fraser Magee Intensive Care Medicine Leave a comment

Early Manipulation of Arterial Blood Pressure in Acute Ischemic Stroke(MAPAS):Results of a Randomized Controlled Trial Luiz Antonio Nasi. Neurocritical Care 2019; doi: https://doi.org/10.1007/s12028-018-0642-5 Clinical Question In adult patients presenting within 12 hours of an acute ischaemic stroke (AIS), which of three targeted and pre-specified systolic blood pressure (SBP) ranges results in an improved functional outcome at 90 days? Background Significant […]

SHoC-ED 3

3 May 2019 Adrian Wong Emergency Medicine, Intensive Care Medicine 2 comments

In patients presenting to the Emergency Department (ED) in cardiac arrest, does a standardised point-of-care ultrasound protocol, compared with usual care, affect the length of resuscitation, frequency of interventions, and clinical outcomes?

Woolum

26 April 2019 Jose Chacko Emergency Medicine, Intensive Care Medicine 3 comments

In patients with septic shock, does the administration of thiamine lead to more rapid lactate clearance and improved clinical outcomes?

EVALD

19 April 2019 David Slessor Intensive Care Medicine Leave a comment

In patients that survive with a good neurological outcome following out-of-hospital cardiac arrest, does 48 hours vs. 24 hours of therapeutic hypothermia, improve memory, attention & executive function at 6 months?