A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
A multicentre evaluation of two intensive care unit triage protocols for use in an influenza pandemic Winston K Cheung. Medical Journal of Australia; August 2012 [3]:178-181. doi:10.5694/mja11.10926] Clinical Question In the event of a viral pandemic, what effect does the use of a triage protocol (specifically the NSW ICU triage protocol) have in increasing ICU bed availability, both in admission […]
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In patients with severe sepsis what is the sensitivity of blood cultures taken after the initiation of antimicrobial therapy?
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In patients requiring emergency out-of-hospital endotracheal intubation, is rocuronium non-inferior to suxamethonium in providing a successful first pass attempt?
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In critically ill, mechanically ventilated patients, does a strategy of no sedation, as compared with light sedation with daily sedation breaks, impact day 90 mortality?
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In patients older than 65-years with vasodilatory hypotension receiving vasopressors, does a target mean arterial pressure (MAP) of 60-65mmHg compared with usual care impact mortality?
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In ICU patients requiring invasive mechanical ventilation, does the use of proton pump inhibitors (PPIs) vs. histamine-2 receptor blockers (H2RBs) for stress-ulcer prophylaxis, reduce 90-day mortality?
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Does treatment with vitamin C, hydrocortisone, and thiamine lead to a more rapid resolution of septic shock compared with hydrocortisone alone?
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In patients with status epilepticus who have been treated with benzodiazepines, is Levetriracetam, Valproate or Fosphenyoin more likely to lead to an absence of seizures and improved responsiveness at 60 minutes?
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In low and moderate risk patients presenting to the Emergency Department with symptoms suggestive of pulmonary embolism (PE), can a higher d-dimer threshold be used to safely exclude pulmonary embolism without the need for imaging?
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Is 5-day oral lefamulin non-inferior to 7-day oral moxifloxacin in the management of community-acquired bacterial pneumonia?
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