APROCCHSS
In critically ill patients with septic shock, does the combination of hydrocortisone plus fludrocortisone therapy reduce 90 day mortality?
Continue reading »Special Topic: Steroids
ADRENAL
In critically ill patients with septic shock, does hydrocortisone compared with placebo, reduce 90 day mortality?
Continue reading »Steroids in Sepsis
In patients with septic shock, do corticosteroids compared to placebo reduce mortality?
This is an editorial blog post in anticipation of the ADRENAL trial results to be presented at #CCR18.
COIITSS
In patients with septic shock who are treated with corticosteroids, does tight glycaemic control (4.44–6.1 mmol/l) compared with less-tight glycaemic control (<8.3 mmol/l) reduce in-hospital mortality?
Continue reading »CRASH-1
In adults with a head injury, do early corticosteroids compared to placebo reduce death and disability?
Continue reading »Meduri
Does a prolonged course of intravenous methylprednisolone improve lung function and reduce mortality in patients with unresolving ARDS
Continue reading »Annane
In patients with septic shock and relative adrenal deficiency does low dose corticosteroids improve 28 day mortality?
Continue reading »REDUCE
Is short-term (5 days) systemic glucocorticoid treatment in patients with COPD exacerbation as good as conventional (14 days) treatment in clinical outcome and does it decrease the overall exposure to steroids?
Continue reading »VSE
In patients in cardiac arrest, does vasopressin + epinephrine during CPR combined with steroid supplementation during and after CPR, improve survival to discharge with a good neurological outcome, in comparison to the use of epinephrine alone?
Continue reading »Meduri
In patients with early ARDS, does continuous methylprednisolone compared to placebo reduce lung injury scores within 7 days?
Continue reading »