LOGICAL – Conservative Oxygen after Cardiac Arrest

Conservative Oxygen for Unresponsive Patients after Cardiac Arrest The LOGICAL Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. NEJM. 2026. doi: 10.1056/NEJMoa2513814 Clinical Question In patients who are unresponsive after cardiac arrest, does limiting oxygen exposure to achieve acceptable oxygenation increase the likelihood of surviving with a favourable functional outcome Background Brain damage and unfavourable […]

Continue reading »

TAVR vs SAVR for severe aortic stenosis

Clinical Question In adults with asymptomatic severe aortic stenosis and low surgical risk, should transcatheter aortic-valve replacement (TAVR) or surgical aortic-valve replacement (SAVR) be recommended as the preferred initial strategy? Background Management of severe aortic stenosis has evolved rapidly over the past decade, driven largely by the expansion of transcatheter aortic-valve replacement into lower- risk and younger patient populations. While […]

Continue reading »