MENDS2
In mechanically ventilated adults with sepsis, does the use of dexmedetomidine, compared with propofol, for continuous sedation improve the number of days alive without delirium or coma?
Continue reading »Tag: Sedation
NONSEDA
In critically ill, mechanically ventilated patients, does a strategy of no sedation, as compared with light sedation with daily sedation breaks, impact day 90 mortality?
Continue reading »ROSE
In patients with moderate to severe ARDS, does a strategy of early neuromuscular blockade with heavy sedation, as opposed to usual care with lighter sedation targets, result in a lower 90 day mortality?
Continue reading »SPICE III
In ventilated, critically ill patients, does the use of dexmedetomidine as the primary sedative agent compared with usual sedative agents effect 90 day mortality?
Continue reading »Skrobik
In delirium free critically ill adult patients receiving sedation, does the addition of nocturnal low dose dexmedetomidine prevent delirium and improve sleep?
Continue reading »MoDUS
In mechanically ventilated patients, does the early administration of simvastatin compared to placebo reduce the incidence of brain dysfunction (delirium and / or coma)?
Continue reading »DESIRE
In ventilated patients with sepsis, does a sedation strategy with dexmedetomidine compared with no dexmedetomidine improve mortality and number of ventilator-free days?
Continue reading »POKER
In adult Emergency Department patients requiring intravenous sedation for noxious procedures, does a combination of propofol and ketamine (ketofol), compared with single-agent propofol, cause fewer adverse respiratory events?
Continue reading »DahLIA
Is Dexmedetomidone effective in reducing the incidence of agitated delirium and days on a ventilator?
Continue reading »Gu
In adult patients with sepsis, severe sepsis or septic shock, is a single dose of etomidate for induction of anaesthesia, compared with any other induction, associated with a difference in mortality?
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