OPTALYSE PE
In patients with intermediate risk PE, do low doses of tPA and short durations of ultrasound facilitated catheter directed thrombolysis, result in a reduction in RV:LV diameter at 48 hours?
Continue reading »Year: 2018
REDUCE Haloperidol
In critically ill adults, does haloperidol 1 mg or haloperidol 2 mg given three times a day compared to placebo reduce mortality?
Continue reading »Woolum
In patients with septic shock, does the administration of thiamine lead to more rapid lactate clearance and improved clinical outcomes?
Continue reading »ICON
In critically ill adults that survive their acute illness, what is the incidence of depression, anxiety and post-traumatic stress disorder?
Continue reading »TICH-2
In adults with acute, spontaneous intra-cerebral haemorrhage (ICH), does the administration of tranexamic acid (TXA) compared to a placebo improve functional status at 90 days?
Continue reading »iPROVE
In adult patients undergoing abdominal surgery, with intermediate-to-high-risk of post-operative pulmonary complications, will an individualised perioperative open-lung ventilation strategy (iPROVE), compared with standard protective ventilation, result in fewer post-operative complications during the first 7 days post surgery
Continue reading »BREATHE
In adult patients on invasive mechanical ventilation who are difficult to wean, does extubation and weaning on non-invasive ventilation compared to weaning on invasive ventilation reduce the time until liberation from mechanical ventilation?
Continue reading »HIGH
In immunocompromised patients with acute hypoxic respiratory failure (AHRF), does the use of high flow oxygen as opposed to standard oxygen therapy, reduce 28 day mortality?
Continue reading »PReVENT
In mechanically ventilated patients without acute respiratory distress syndrome (ARDS), does a low tidal volume ventilation strategy (6mL/Kg), compared to intermediate tidal volume strategy (10mL/Kg), reduce the number of ventilator-free and alive days at day 28?
Continue reading »MIND-USA
In delirious adult ICU patients, does the administration of haloperidol or ziprasidone reduce the duration of delirium when compared with placebo?
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