A compendium of critical appraisals in Intensive Care Medicine research and related specialties
In patients undergoing cardiac surgery, who have a moderate-to-high risk of death, does a restrictive transfusion strategy compared with a liberal strategy impact on a composite outcome of death, myocardial infarction, stroke and acute kidney injury requiring dialysis
Continue reading »
In adult patients undergoing elective coronary-artery surgery does tranexamic acid (TXA) compared to a placebo increase the risk of death or thrombotic complications within the first 30 days after surgery?
Continue reading »
In adults undergoing elective coronary artery graft surgery does the administration of aspirin prior to surgery compared to a placebo result in increased mortality or thrombotic complications?
Continue reading »
In patients with LVEF <35% undergoing cardiac surgery does levosimenden compared with placebo reduce the incidence of a composite outcome of: death at day 30; renal replacement therapy at day 30; perioperative myocardial infarct at day 5; and use of mechanical assist device at day 5
Continue reading »In adults undergoing cardiac surgery, does a restrictive transfusion strategy (Hb > 75 g/l) compared to a liberal transfusion strategy (Hb > 90 g/l) lead to fewer infections and ischaemic events within 3 months?
Continue reading »