A compendium of critical appraisals in Intensive Care Medicine research and related specialties
In patients requiring rapid sequence intubation (RSI) in the emergency department does the addition of fentanyl to ketamine and rocuronium reduce the frequency of patients having a systolic blood pressure (SBP) outside of a target range of 100-150mmHg?
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In neonates undergoing elective endotracheal intubation, does nasal high-flow therapy compared with standard care, improve 1st pass success without physiological instability?
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In critically ill adults, does the use of an intubating stylet compared to tracheal tube alone, increase first-attempt successful intubation?
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In adult patients undergoing rapid sequence intubation for emergency surgery, does pre-oxygenation with high-flow nasal oxygen, compared with standard face-mask oxygen, reduce the incidence of oxygen desaturation?
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In patients requiring emergency out-of-hospital endotracheal intubation, is rocuronium non-inferior to suxamethonium in providing a successful first pass attempt?
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In adult ICU patients undergoing tracheal intubation, does bag mask ventilation (BMV) between induction and laryngoscopy reduce the risk of hypoxaemia?
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In patients undergoing rapid sequence anaesthesia induction, does the use of cricoid pressure vs. a sham procedure, prevent pulmonary aspiration?
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In adults suffering out-of-hospital non-traumatic cardiac arrest, does a strategy of airway management initially with laryngeal tube (LT) compared to endotracheal intubation (ETI) reduce mortality at 72 hours?
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In adult patients with non-traumatic out-of-hospital cardiac arrest, does a supraglottic airway device compared with tracheal intubation as the initial advanced airway management strategy, improve functional neurological outcome?
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In critically ill patients undergoing emergency intubation, does the ramped position compared to sniffing position reduce the incidence of oxygen desaturation?
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