IDEAL-ICU
patients with septic shock and severe acute kidney injury, does early vs. delayed renal replacement therapy improve 90 day mortality?
Continue reading »Tag: Renal
Atan
In critically ill patients on noradrenaline for haemodynamic support, who required hemofiltration for AKI, does the use of a high cutoff hemofilter compared with a standard hemofilter impact the median hours of noradrenaline-free time at day 7?
Continue reading »BICAR-ICU
In critically ill patients with severe metabolic acidaemia (pH ≤7⋅20), does the infusion of sodium bicarbonate, compared with no infusion, to reach and maintain a targeted pH of 7⋅30 decrease the primary composite outcome of mortality by day 28 or the presence of at least one organ failure at day 7?
Continue reading »SALT-EM
In non-critically ill adult patients admitted to hospital from the Emergency Department, does the administration of a balanced salt solution compared with normal saline, reduce hospital free days to day 28?
Continue reading »SMART
In critically ill patients does the administration of balanced crystalloids compared with saline, reduce a 30 day composite outcome of death, new renal replacement therapy or persistent renal dysfunction?
Continue reading »ELAIN FOLLOW-UP
In adult critically ill patients, with acute kidney injury, does early initiation of RRT compared to delayed initiation of RRT reduce the composite endpoint of MAKE365; consisting of death, RRT and persistent renal dysfunction at one year?
Continue reading »PRESERVE
In high-risk patients undergoing angiography, does the administration of bicarbonate and/or acetylcysteine, compared with placebo, prevent major adverse events and acute kidney injury?
Continue reading »SPARK
In critically ill patients, with mild renal failure, does furosemide infusion compared to placebo worsen kidney function?
Continue reading »AMACING
In high-risk patients receiving contrast medium, does prophylactic hydration with normal saline compared to no prophylaxis impact the rate of contrast-induced nephropathy?
Continue reading »RENAL Trial
In critically ill adults requiring renal replacement therapy, does higher intensity dialysis compared to lower intensity dialysis reduce mortality?
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