Luke Collett

DOREMI

2 September 2021 Luke Collett Intensive Care Medicine Leave a comment

Milrinone as compared with Dobutamine in the Treatment of Cardiogenic Shock Matthew. N Engl J Med 2021; 385:516-525, doi: 10.1056/NEJMoa2026845 Clinical Question In patients with cardiogenic shock, does milrinone as compared with dobutamine improve the composite outcome of in-hospital death, resuscitated cardiac arrest, receipt of cardiac transplant or mechanical circulatory support, non-fatal myocardial infarction, cerebrovascular event or renal replacement therapy? […]

HOT-ICU

25 February 2021 Luke Collett Intensive Care Medicine Leave a comment

In patients with acute hypoxaemic respiratory failure, does a lower vs higher oxygenation target reduce mortality at 90 days?

REDECAP

24 September 2020 Luke Collett Intensive Care Medicine Leave a comment

In conscious critically ill patients who have had a tracheostomy inserted as part of their ICU stay and have been weaned from mechanical ventilation, does an assessment of readiness for decannulation that is based on suctioning frequency, when compared to an assessment based on tracheostomy capping, result in a shorter time to successful decannulation?

LOCO2

4 September 2020 Luke Collett Intensive Care Medicine, Summaries Leave a comment

In patients with acute respiratory distress syndrome (ARDS), does conservative vs. liberal oxygen reduce death at 28 days?