continuous renal replacement therapy

LIBERATE-D – Conservative Dialysis Strategy

1 May 2026 Samuel Brockbank Intensive Care Medicine, Summaries Leave a comment

LIBERATE-D – A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury: The Liberation From Acute Dialysis (LIBERATE-D) Randomized Clinical Trial Liu KD, Siew ED, Tuot DS, Vijayan A, Umemoto GM, Birkelo BC, et al. JAMA. 2026;335(4):326–335. doi:10.1001/jama.2025.21530 Clinical Question In clinically stable adults with AKI-D receiving IHD and expected to require outpatient dialysis after discharge, does […]

PROTECTION – Amino Acids for Kidney Protection

In adult patients scheduled for cardiac surgery with cardiopulmonary bypass does infusion of a balanced solution of amino acids, commencing at the time of surgery, compared with balanced crystalloid alone (Ringer’s Lactate) reduce the incidence of acute kidney injury (AKI)?

STARRT-AKI

17 July 2020 Celia Bradford Intensive Care Medicine 5 comments

Standard versus Accelerated Initiation of Renal Replacement Therapy Wald R, Bagshaw S. NEJM July 16 2020 doi:10.1056/NEJMoa2000741 Clinical Question In critically ill patients with severe acute kidney injury, does accelerated initiation of renal replacement therapy compared to standard initiation improve 90 day survival? Background Acute Kidney Injury (AKI) is common in critically ill patients and some case series suggest up […]