VENT-AVOID – Extracorporeal Carbon Dioxide Removal to Avoid Invasive Ventilation During COPD Exacerbations

Extracorporeal Carbon Dioxide Removal to Avoid Invasive Ventilation During Exacerbations of Chronic Obstructive Pulmonary Disease: VENT-AVOID Trial – A Randomized Clinical Trial Duggal et al. 2024; American Journal of Respiratory and Critical Care Medicine March 1, 2024 Pages xv-616 Clinical Question In patients with acute exacerbations of COPD who are either failing noninvasive ventilation (NIV) or failing to wean from […]

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NIV vs HFNC to prevent re-intubation in patients with obesity

Humidified Non-Invasive Ventilation versus High-Flow Therapy to Prevent Reintubation in Patients with Obesity Hernández et al. AJRCCM 2025. DOI: 10.1164/rccm.202403-0523OC Clinical Question In obese adult patients at intermediate risk for hypoxaemic extubation failure, does non-invasive ventilation (NIV) therapy with active humidification compared to use of high-flow nasal oxygen (HFNO or HFNC) reduce all-cause reintubation within 7 days after extubation? Background […]

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