Emergency Evidence Updates – May 2025

Randomised Controlled Trials

A non-inferiority randomised controlled trial of a Shorter Acetylcysteine Regimen for Paracetamol Overdose – the SARPO trial.  Journal of Hepatology

Association of central capillary refill time with mortality in adult trauma patients: a secondary analysis of the crash-2 randomised controlled trial data  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Dorsal Digital Nerve Block Versus Ultrasound-Guided Selective Peripheral Nerve Block for Finger Analgesia: A Randomized Controlled Study  The Journal of Emergency Medicine

Impact of rescuer position, arm angle, and anthropometric variables on muscle fatigue during cardiopulmonary resuscitation: an international multicentric randomized crossover simulation study  Resuscitation Plus

Intraosseous vs. intravenous access during out-of-hospital cardiac arrest: a Bayesian secondary analysis of a randomised clinical trial  Resuscitation

Oral Syringe Versus Drug Pacifier for Delivery of Oral Antipyretic Medication: A Randomized Controlled Trial  Journal of Emergency Nursing

Outcomes of Pediatric Facial Laceration Repair Using 5-0 Fast Absorbing Gut Sutures With and Without Overlying Adhesive Strips: A Randomized Controlled Trial  Pediatric Emergency Care

Preoxygenation With and Without Positive End-Expiratory Pressure in Lung-Healthy Volunteers – A Randomized Clinical Trial  JAMA Network Open

Relationship between applied face mask force and mask leak during simulated neonatal ventilation: a randomised simulation study  ADC Fetal & Neonatal Edition

Role of Preoperative Antibiotic Treatment While Awaiting Appendectomy – The PERFECT-Antibiotics Randomized Clinical Trial  JAMA Surgery

The Effect of Using Thermomechanical Stimulation and Virtual Reality Glasses During Peripheral Intravenous Catheterization on Pain and Patient Satisfaction: A Randomized Controlled Trial  Journal of Emergency Nursing

The Impact of Suctioning on Oxygenation During RSI in the Emergency Department: A Multi-Center Pilot Randomized Controlled Trial  The Journal of Emergency Medicine

Virtual Reality Glasses Reduce Patients’ Anxiety During Emergency Surgical Procedures Under Local Anesthesia: A Randomized Controlled Clinical Study  Journal of Emergency Nursing

 

NICE

COVID-19 rapid guideline: managing COVID-19 NG191

 

Other Guidance/Reports

Blood product administration in the prehospital setting: a multisociety consensus statement  Journal of Anesthesia, Analgesia and Critical Care

Guidelines for the management of emergencies and critical illness in pediatric and adult patients with sickle cell disease  Annals of Intensive Care

Management and Prevention of Hypersensitivity Reactions to Radiocontrast Media: A Consensus Statement from the American College of Radiology and the American Academy of Allergy, Asthma & Immunology  Radiology

Platelet Transfusion – 2025 AABB and ICTMG International Clinical Practice Guidelines  JAMA

RCEM

 

Primary Research

Prehospital

Association of prehospital invasive blood pressure measurement and treatment times of intubated patients with suspected stroke – a retrospective study  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Automated Cardiac Arrest Detection and Emergency Service Alerting Using Device-Independent Smartwatch Technology: Proof-of-Principle  Resuscitation

Identifying and profiling prearrival characteristics of avoidable emergency department visits transported by paramedics: a cohort study using linked prehospital and hospital data  Emergency Medicine Journal

Navigating emotions, communication, and pain during prehospital labour: a mixed-methods survey with emergency ambulance services  BMC Emergency

Pre-hospital ECPR for refractory cardiac arrest – The PRECARE pilot feasibility study  Resuscitation

 

General

A Physiotherapy-Led Emergency Department Guideline (PLEDGE) for Patients Presenting With Low Back Pain: Pre- and Post-Implementation Study  Emergency Medicine Australasia

Barriers to the success of cardiopulmonary resuscitation teams in emergency departments: A perspective from nurses  BMC Emergency Medicine

Beyond Nurse Efficiency: A Multilevel Analysis of Nurse, Contextual, and Patient-Related Factors in Triage Duration  Journal of Emergency Nursing

Comparison of Glasgow coma scale, motor component, eye component, and simplified motor scale for predicting trauma outcomes: a 13-year multicenter retrospective cohort study  BMC Emergency Medicine

Decision analysis model of rapid versus deferred antibiotic initiation in patients with suspected sepsis in the emergency department  Intensive Care Medicine

Designing acceptable services to better serve lower-acuity presenters to emergency departments: a latent class analysis of a discrete choice experiment in Australia  Emergency Medicine Journal

Emergency department use of airway adjuncts in the setting of endotracheal intubation for traumatic injury  The Journal of Emergency Medicine

Evaluating the Accuracy of Google Translate in Emergency Department Discharge Instructions  The Journal of Emergency Medicine

Evaluation of a Novel Clinical Assistant Model of Care on Patient Flow and Emergency Department Length of Stay  Emergency Medicine Australasia

Evaluation of a virtual emergency care service to avoid unnecessary emergency department presentations and provide specialist-led definitive care  Emergency Medicine Australasia

Formative Evaluation to Inform Implementation of Sepsis Bundles in Emergency Departments  Annals of Emergency Medicine

Investigation of Emergency Nurses in Detecting Foreign Bodies in Soft Tissues With Ultrasonography: A Manikin Study  Journal of Emergency Nursing

Nurse-Initiated X-Ray Requests for Extremity Trauma in the Emergency Department: A Single-Center, Prospective, Before-and-After Cohort Study  Journal of Emergency Nursing

Nurses’ Perceptions of an Intervention Program to Improve Miscarriage Care in Emergency Departments  Journal of Emergency Nursing

Prognostic factor in extracorporeal cardiopulmonary resuscitation for refractory in- and out-of-hospital cardiac arrest  The Journal of Emergency Medicine

Removing systolic blood pressure from the National Early Warning Score (NEWS) for mortality prediction: an observational study  Emergency Medicine Journal

The association between urgency level and hospital admission, mortality and resource utilization in three emergency department triage systems: an observational multicenter study  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

TeLePhone Respiratory (TeLePoR) score to assess the risk of immediate respiratory support through phone call for acute dyspnoea: a prospective cohort study  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

 

Paediatric

A Descriptive Analysis of the Reliability of the Broselow Tape for Use in the US Pediatric Trauma Population – A Trauma Quality Improvement Program Study  Pediatric Emergency Care

A Qualitative Study Exploring Adolescent and Caregiver Perspectives of Electronic Suicide Screening in the Emergency Department  Annals of Emergency Medicine

Association of Respiratory Pathogen Panel Testing on the Proportion of Emergency Department Revisits in Children With Symptoms of Upper Respiratory Illness  Pediatric Emergency Care

Can Caregivers Reliably Assess Their Child’s Heart Rate and Respiration Rate Using Smartphone or Smartwatch Applications?  Pediatric Emergency Care

Complete atrioventricular block during neonatal intubation: a case report  Resuscitation Plus

Diagnostic accuracy of point-of-care cranial ultrasound for initial assessment of infants without suspected trauma in the pediatric emergency department  The Journal of Emergency Medicine

Efficacy of Alternative Chest Compression Methods Performed by Small Rescuers  Pediatric Emergency Care

Factors associated with severe bacterial infection in infants between 91- and 120-days old admitted to the pediatric emergency department  BMC Pediatrics

Impact of Eliminating Oral Contrast on Computed Tomography Abdomen/Pelvis Throughput in the Pediatric Emergency Setting – A Multisite Analysis  Pediatric Emergency Care

Magnet ingestion in children in the United Kingdom: a national prospective observational surveillance study  Archives of Disease in Childhood

Point-of-Care Ultrasound Detection of Pseudoaneurysms in Pediatric Patients – A Multicenter Case Series  Pediatric Emergency Care

Posterior Cerebral Artery Stroke in a Pediatric Patient  The Journal of Emergency Medicine

Presentation, Evaluation, and Outcomes of Infants Under Three Months with Skull Fractures  The Journal of Emergency Medicine

Prevalence of serious bacterial infections and performance of inflammatory markers in febrile infants with and without proven viral illness  Emergency Medicine Journal

Quality of Life for Children With Mental and Behavioral Health Emergencies in the Pediatric Emergency Department  Pediatric Emergency Care

Spontaneous intracranial hypotension and dural tear in a pediatric patient after minor fall: A case report  The Journal of Emergency Medicine

Timing for Assessment of Bleeding Diathesis in Pediatric Blunt Traumatic Brain Injury  Pediatric Emergency Care

Triage Pediatric Age-Adjusted Shock Index as a Predictor of Hospital Admission  The Journal of Emergency Medicine

 

Adult

A novel stroke mimic prediction score during in-hospital triage for suspected stroke patients: The Stroke Mimics Score (SMS)  European Stroke Journal

Acidosis as a promising early indicator of mortality among point-of-care parameters and vital signs in non-traumatic critically ill patients  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Association between age and length of stay in the emergency department in a tertiary care hospital: a retrospective observational study  Emergency Medicine Journal

Atrial fibrillation patients presenting to an emergency department successfully managed with a next-day community follow-up pathway: A before-and-after cohort study  Emergency Medicine Australasia

Diagnosis of Cardiac Transplant Rejection Using Point-of-Care Ultrasound  The Journal of Emergency Medicine

Diagnostic Accuracy of the EDACS and EDACS-ADP Scores for Risk Stratification in Patients Presenting with Chest Pain in the Emergency Department  The Journal of Emergency Medicine

Does frailty scoring help to predict outcomes in older patients with major trauma? A retrospective study at a major trauma centre  Emergency Medicine Australasia

Early ADL ability assessment and cognitive screening as markers of post-discharge outcomes after surviving an out-of-hospital cardiac arrest. A prospective cohort study  Resuscitation

Intravenous Tenecteplase before Thrombectomy in Stroke  NEJM

Intubations for drug overdose: can we predict short intubations?  The Journal of Emergency Medicine

Neurologic etiologies of cardiac arrest are associated with early withdrawal of life-sustaining therapy  Resuscitation

Point of Care Echocardiography and Regional Wall-Motion Abnormalities in Acute Coronary Syndromes  The Journal of Emergency Medicine

Proximal venous ultrasound with risk stratification safely excludes deep venous thrombosis in emergency department routine care: an observational study  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Push-Dose Epinephrine Utilization in the Emergency Department – A Multi-Center Study   The Journal of Emergency Medicine

Remimazolam for procedural sedation in the emergency department: a prospective study of effectiveness and patient satisfaction  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

The Interfascial Plane Block: An Adjunctive Ultrasound-Guided Block for Proximal Humerus Fracture and Fracture Dislocation Anesthesia and Analgesia in the Emergency Department  The Journal of Emergency Medicine

The significance of possible non-occlusive mesenteric ischemia in relation to neurological outcomes in patients with refractory cardiac arrest – Secondary analysis of the Prague OHCA study  Resuscitation

Urine Amphetamine Screening and Suicidality: A 5-year Retrospective Analysis of Emergency Department Patients  The Journal of Emergency Medicine

 

Metadata

Summary author: Rebecca Howes
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash

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