Emergency Evidence Updates – December 2025
Randomised Controlled Trials
10% Lidocaine vs. 1% Diclofenac Spray in Radial Arterial Blood Gas Sampling: A Randomized, Double-Blind, Placebo-Controlled Trial Using Perfusion Index The Journal of Emergency Medicine
Point-of-care decision rule for antibiotic prescriptions in young children with fever without source: an open cluster randomised trial Archives of Disease in Childhood
The Limit of Detection in the Emergency Department Trial (LEGEND): A Stepped-Wedge Cluster Randomized Trial to Rule Out Acute Myocardial Infarction and Reduce Hospital Length of Stay for Patients Presenting to the Emergency Department Annals of Emergency Medicine
Ultrasound-Guided Regional Anesthesia by Emergency Physicians for Hip Fractures and Delirium – A Randomized Clinical Trial JAMA Network Open
NICE
Child maltreatment: when to suspect maltreatment in under 18s CG89
Other Guidance/Reports
PIER
- Children’s Cancer Referral Pathway into Southampton Principle Treatment Centre (PTC) V1.0
- Position Statement on Respiratory PCR testing in children
- Management of Paediatric Influenza – Updated
- Paediatric Hypertension – Updated
- Initiation of Acute NIV (CPAP/BiPAP)
Primary Research
Prehospital
Association between location of prehospital intubation, complication rates and time intervals Emergency Medicine Journal
Delays in chest compressions during out-of-hospital cardiac arrest: carotid versus subxiphoid point of care ultrasound Resuscitation
Early Recognition and Management of Severe Sodium Nitrite Intoxication: A Case Report Emphasizing Prehospital Administration of Methylene Blue Prehospital Emergency Care
“It’s about maintaining a calm and reassuring presence”: a qualitative study about ambulance clinicians’ experiences of caring for patients with breathlessness BMC Emergency Medicine
Pre-hospital red cell transfusion and patient outcomes after trauma Trauma
General
Association between catchment-area demographics and emergency department presentation rates and delays: a national cross-sectional study Emergency Medicine Journal
Computer-vision Based Recognition of Cervical Spine Stabilization during Trauma Resuscitation Injury
Evaluating the impact of NHS strikes on patient flow through emergency departments Emergency Medicine Journal
External validation of the modified Brain Injury Guidelines: an observational study BMC Emergency Medicine
Impact of Transition Units on Emergency Department Crowding: A Before-and-After Study The Journal of Emergency Medicine
Implementation of “STAMP” at Triage to Prevent Workplace Violence in the Emergency Department: A Quality Improvement Project Journal of Emergency Nursing
Inter-rater agreement of respiratory distress observation scale measurement between physicians and nurses in the emergency department BMC Emergency Medicine
Nudging Emergency Department Clinicians to Reduce Unnecessary Diagnostic Test Ordering: A Multi-Arm Vignette-Based Experiment Emergency Medicine Australasia
Shifting patterns in emergency department attendance: a time series analysis Emergency Medicine Journal
Understanding corridor and escalation area care in 165 UK emergency departments: a multicentre cross-sectional snapshot study Emergency Medicine Journal
Working Environment in a Virtual Emergency Department: A Cross-Sectional Study Emergency Medicine Australasia
Paediatrics
An Assessment of Child Life Service and Pain Management in Pediatric Trauma Patients Pediatric Emergency Care
Comparative Evaluation of Different Pediatric Early Warning Scores in Predicting Clinical Outcomes in Pediatric Emergency Observation Units Pediatric Emergency Care
Delayed Effect After Procedural Sedation With Oral Ketamine and Midazolam – A Case Series Pediatric Emergency Care
Don’t Get MAD – Managing Agitation With De-Escalation Training in a Pediatric Emergency Department Pediatric Emergency Care
Infant emergency department visits, readmission, and mortality by maternal anxiety disorder during pregnancy occurring with and without other mental health conditions: a retrospective cohort study BMC Pregnancy and Childbirth
Mindful Scanning – Lung Point of Care Ultrasound for Diagnosing Retroscapular Pneumonia in Children Pediatric Emergency Care
Pediatric Epididymitis With Atypical Evolution – A Case of Testicular Necrosis and Review of Management Strategies Pediatric Emergency Care
Practice—Change Pathway to Reduce Procedural Distress During Intussusception Reduction—A Quality Improvement Initiative Pediatric Emergency Care
Predictors of Osteochondral Fractures Following Patellar Dislocation in the Pediatric Emergency Department Pediatric Emergency Care
Real-World Rapid Brain Magnetic Resonance Imaging Utilization in the Pediatric Emergency Setting A 10-Year Cross-Sectional Study Pediatric Emergency Care
Risk Factors for Pediatric Deep Neck Infection Revisit After Emergency Department Discharge for Pharyngitis or Localized Neck Symptoms Annals of Emergency Medicine
The Effect of a Rapid Assessment Team on Pediatric Emergency Medicine Department Operations and Throughput Pediatric Emergency Care
Adult
Association between hip dislocation in pelvic fracture and concomitant knee ligament injuries Injury
Bleeding control in catastrophic blunt pelvic trauma using the abdominal aortic and junctional tourniquet in a civilian level I trauma center: A case report Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Early ECMO Support in Bupropion-Induced Cardiogenic Shock: A Case Series The Journal of Emergency Medicine
Early Intensive Blood Pressure Reduction After Intracerebral Hemorrhage Is Associated With Worse Functional Outcome: The Risk of Overshooting Blood Pressure Goals Annals of Emergency Medicine
Evaluating the Effectiveness of the Integrated Geriatric Emergency Medicine Short Stay Unit Model of Care: A Retrospective Cohort Study Emergency Medicine Australasia
Impact of rhythm changes during CPR on ECPR outcomes: an ELSO Registry study Resuscitation
Inter-rater Reliability of Point-of-Care Ultrasound During Out-of-Hospital Cardiac Arrest: An Ancillary Analysis of the observational prospective ACE Trial Resuscitation Plus
Predicting triage levels in patients presenting with cardiac-related symptoms: a comparison of supervised machine learning methods BMC Emergency Medicine
Predictors of Contrast Extravasation in The Emergency Department: A Case-Control Multi-Center Retrospective Study The Journal of Emergency Medicine
Respiratory National Early Warning Score for 28-day mortality prediction in suspected sepsis patients in the emergency department BMC Emergency Medicine
Risk Stratification of Patients Presenting With Chest Pain in the Emergency Department: A Quality Improvement Initiative Journal of Emergency Nursing
Serum lactate and carboxyhemoglobin as predictors of hyperbaric oxygen therapy in carbon monoxide poisoning: a retrospective study BMC Emergency Medicine
SVEAT score for early risk stratification of acute chest pain: a multicenter study BMC Emergency Medicine
Uncomplicated Acute Alcohol Intoxication in the Emergency Department: A 12-Year Retrospective Study to Understand Practice Change in Intravenous Fluid Usage and Patient Outcomes Emergency Medicine Australasia
Use of Single Lead ECG to Assist Cardioversion in Atrial Fibrillation in the Emergency Department (SELECTED): Proof of Concept Study Emergency Medicine Australasia
When the Skin Lies: Occult Scalp Necrotizing Fasciitis After Blunt Head Trauma The Journal of Emergency Medicine
Metadata
Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash
