Emergency Evidence Updates – January 2026
Randomised Controlled Trials
A Randomized, Dose-Finding Study of Sphenopalatine Ganglion Block With Bupivacaine for Emergency Department Patients With Headache Annals of Emergency Medicine
Automated titration of nasal high flow oxygen in the emergency department: a randomised controlled trial Emergency Medicine Journal
Early Cessation of Acetylcysteine Treatment After Paracetamol Overdose (NACSTOP 2): A Non-Inferiority Randomised Controlled Trial Medical Journal of Australia
Effect of Direct-from-blood Bacterial Testing on Antibiotics Administration in Adults Presenting With Acute Infection: A Randomized Trial Clinical Infectious Diseases
Other Guidance/Reports
Penicillin Allergy and De-Labelling PIER
Research priorities for paediatric procedural sedation in emergency medicine Emergency Medicine Journal
Management of Adult Patients who attend Emergency Departments after Sexual Assault and-or Rape(January 2026) RCEM
Management of patients with Haemophilia in Emergency Departments(January 2026) RCEM
UK consensus guidelines for multidisciplinary care of children and young people with achondroplasia: a modified Delphi process Archives of Disease in Childhood
Primary Research
Prehospital
A nationwide Scottish cohort study of the association between pre-existing mental illness and out-of-hospital cardiac arrest survival Resuscitation Plus
Embedding a Virtual Emergency Department Pathway Within Emergency Medical Services Secondary Triage for People Living in Residential Aged Care Prehospital Emergency Care
MetoksyKval: the extent of pre-hospital methoxyflurane administration for acute traumatic pain: focus on economic impact and rationale for use Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Mismatch Between Antecubital Peripheral Intravenous Catheter Insertion and Contrast CT Use in the Emergency Department: A Retrospective Analysis Emergency Medicine Australasia
Oral transmucosal fentanyl citrate analgesia in prehospital trauma care: a retrospective observational cohort study focusing on age and gender differences Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Prehospital diagnostic performance of emergency physicians in identifying blunt traumatic pneumothorax requiring early decompression BMC Emergency Medicine
Prehospital factors associated with ICU admission in drowning patients: a retrospective multicenter cohort study in a French coastal region BMC Emergency Medicine
Validation of the Modified Sequential Organ Failure Assessment Score for Early Clinical Deterioration in Prehospital Patients with Seizures: A Multicenter Cohort Study Journal of Emergency Nursing
General
Analysis of Initial Emergency Department Ventilator Settings in Accordance with Ability to Oxygenate The Journal of Emergency Medicine
Evaluating the Feasibility, Acceptability, and Preliminary Clinical Efficacy of a Digital Self-Management Intervention in the Emergency Department: A Pilot Study Journal of Emergency Nursing
Factors associated with the phenomenon of overcrowding in the emergency department: a retrospective cohort study BMC Emergency Medicine
IN SITU: Evaluation of the feasibility and impacts of in situ simulation in emergency medicine, a mixed method study Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Predictive criteria for oesophageal perforation in patients with pneumomediastinum: can invasive diagnostic modalities be avoided? Emergency Medicine Journal
Reducing time from presentation to diagnosis of scaphoid fractures with cone beam CT: a before-and-after study Emergency Medicine Journal
The Effect of Progressive Muscle Relaxation Exercises on Fatigue Severity and Sleep Quality Among Emergency Nurses: A Self-Controlled Quasi-Experimental Study Journal of Emergency Nursing
ULTRASOUND-GUIDED TRUNCAL BLOCKS FOR TUBE THORACOSTOMY ANALGESIA IN THE EMERGENCY DEPARTMENT The Journal of Emergency Medicine
Paediatric
A Novel Approach Using Relative Value Units to Quantify Workload and Its Association With Patient and Family Experience in the Pediatric Emergency Department Pediatric Emergency Care
Comparison of Diagnostic Imaging Patterns Between Pediatric and Adult Trained Physicians in Adolescent Trauma Activations Pediatric Emergency Care
Decreasing Door-to-Analgesia Time: Increasing Use of Sickle Cell Pain Management Pathway Journal of Emergency Nursing
Dexamethasone Treatment Regimen and Clinical Outcomes in Children With Asthma Exacerbations Annals of Emergency Medicine
ED Lung Ultrasound of Suspected Atelectasis and Assessment of Reaeration in Children – A Case Series Pediatric Emergency Care
Experiences of Trans and Gender Diverse Youth Accessing Emergency Departments: Results of a Community-Designed Questionnaire Journal of Emergency Nursing
High Flow Nasal Cannula Use in Bronchiolitis – Predicting Need for Early Escalation of Care Pediatric Emergency Care
Inhaled L-Epinephrine As a Rescue Therapy in Critical Bronchiolitis Critical Care Explorations
Interrater Reliability in the Triage of Children With Mental and Behavioral Health Symptoms Using Two Triage Systems Journal of Emergency Nursing
Paediatric Ketone Measurement and Intervention in Non-Diabetic Patients in Australasian Emergency Departments: A PREDICT Clinician Survey Emergency Medicine Australasia
Reduced overtriage is associated with increased patient flow at pediatric emergency department Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Reversible causes of death and the potential benefit of invasive emergency techniques in paediatric and adolescent trauma: a 12-years retrospective forensic analysis BMC Emergency Medicine
Screening Pediatric Trauma Patients for Blunt Cerebrovascular Injury Using the McGovern Score: A Retrospective Cohort Study Pediatric Emergency Care
Succinylcholine Versus Rocuronium for Pediatric Rapid Sequence Intubation in the Emergency Department Pediatric Emergency Care
Suspected Pediatric Appendicitis Management in the Emergency Department
A Prospective Observational Study in an Australian Pediatric Emergency Department Pediatric Emergency Care
Ultrasound-Based Prediction Model for Air Enema Failure in Pediatric Ileocolic Intussusception – Comparison of Point-of-Care Ultrasound and Radiologist-Performed Ultrasound Pediatric Emergency Care
Adult
Acidemia predicts mortality independently of lactate levels in patients after cardiac arrest Resuscitation Plus
Association between emergency department bed occupancy rate and in-hospital cardiac arrest in the emergency department: a retrospective study BMC Emergency Medicine
Association between polypharmacy at the emergency department and long-term mortality in critically ill older patients receiving mechanical ventilation: a single-center retrospective cohort study BMC Emergency Medicine
d-Dimer With the Aortic Dissection Detection Risk Score May Improve Patient Selection for Acute Aortic Syndrome Diagnostic Imaging Emergency Medicine Australasia
Defibrillation in patients with accidental hypothermia and core temperatures ≤30°C – A retrospective observational study Resuscitation
Emergency Department Predictors of Mortality and Adverse Outcomes in Upper Gastrointestinal Bleeding: A Five-Year Retrospective Cohort Study The Journal of Emergency Medicine
Emergency Nursing Assessment in a Patient With a Hand Arteriovenous Fistula Caused by a Fishbone: A Case Report Journal of Emergency Nursing
Evaluating the Diagnostic Accuracy of Point-of-Care Ultrasound for Long Bone Fractures in the Emergency Department Journal of Emergency Medicine
External validation of the CRASS score for predicting good neurological outcome in out-of-hospital cardiac arrest: analysis from cardiac-origin and non-cardiac origin cohorts BMC Emergency Medicine
Frequency of computed tomography scans in Crohn’s disease patients in the emergency department Inflammatory Bowel Diseases
Impact of Bedside Ultrasound on Patient Anxiety in Acute Cholecystitis: A Comparative Observational Study Journal of Emergency Nursing
Integrating physiotherapy into the emergency department for acute low back spasm: a retrospective comparative study Physiotherapy Theory and Practice
Myoglobin-to-creatine kinase ratio enhances prediction of acute kidney injury in rhabdomyolysis Emergency Medicine Journal
Optimal timing of antibiotics administration for sepsis or septic shock in the emergency department BMC Emergency Medicine
Presepsin for sepsis diagnosis in emergency departments: a multicentre study Emergency Medicine Journal
Symptom Trajectories of People With Low Back Pain Presenting to the Emergency Department: Insights From the BACK TrAC Digital Care Pathway Journal of Emergency Nursing
Tirzepatide-Associated Euglycemic Diabetic Ketoacidosis in the Absence of SGLT2 Inhibitor Use: A Case Report The Journal of Emergency Medicine
Ultrasound Evaluation of Lens Dislocation with Iridodonesis The Journal of Emergency Medicine
Under-investigation and delays experienced by females presenting with chest pain to Emergency Departments: a study of five linked Canadian hospitals. The Journal of Emergency Medicine
Use of Point-of-Care Ultrasound During Cardiac Arrest in the Emergency Department: A Multicentre Retrospective Study Emergency Medicine Australasia
Why I Left the Emergency Department Before Receiving Care (Did Not Wait): A Cross-Sectional Study Emergency Medicine Australasia
Metadata
Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash
