Emergency Evidence Updates – November 2025
Randomised Controlled Trials
A randomized control trial comparing Falls Reduction for Elderly Emergency Department (FREED) interventions and usual care BMC Emergency Medicine
Earmuff and eye mask in the treatment of acute primary headache in emergency department: a randomized controlled open label study BMC Emergency Medicine
Effectiveness of pericapsular nerve group block for hip fracture pain management in the emergency department: results of the ED-PENG-B randomised controlled trial BMC Emergency Medicine
Hospital and long-term outcomes for subglottic suction and polyurethane cuff versus standard endotracheal tubes in emergency intubation (PreVent 2): a randomised controlled phase 2 trial The Lancet Respiratory Medicine
NICE
Suspected sepsis in people aged 16 or over: recognition, assessment and early management
Suspected sepsis in under 16s: recognition, diagnosis and early management
Other Guidance/Reports
A broken promise: the crisis of mental health care in emergency departments British Journal of Nursing
Acute Care of Patients with Moderate Respiratory Distress: Recommendations from an American College of Emergency Physicians Expert Panel Western Journal of Emergency Medicine
Top three priorities for artificial intelligence integration into emergency, critical, and perioperative medicine: an interdisciplinary clinical expert consensus Journal of Anesthesia, Analgesia and Critical Care
Cochrane
Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection
Primary Research
Prehospital
Pre-hospital blood transfusion in non-traumatic major haemorrhage: a retrospective observational study Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Prehospital thrombolysis with tenecteplase in out-of-hospital cardiac arrest: a retrospective cohort study Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Successful prehospital extracorporeal cardiopulmonary resuscitation in pediatric cardiac arrest – a case report Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
General
A comparison of clinical prediction scores for massive traumatic hemorrhage Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Ambient Artificial Intelligence Versus Human Scribes in the Emergency Department Annals of Emergency Medicine
Comparative evaluation of the Manchester Triage System and emergency severity index in predicting critical events in the emergency department BMC Emergency Medicine
Diagnostic accuracy of E-FAST examination performed by newly trained emergency physicians and its impact on clinical outcomes BMC Emergency Medicine
Effects of forward-leaning cardiopulmonary resuscitation on chest compression quality and rescuer fatigue BMC Emergency Medicine
Individual Survey Items in Emergency Department Patient Experience Surveys Have Limited Ability to Distinguish Unique Aspects of Care Annals of Emergency Medicine
Innovative Nurse, Quality Care: Individual Innovativeness and Caring Behaviors Among Pediatric Emergency Nurses—A Cross-Sectional Study Journal of Emergency Nursing
Nursing-Led Quality Improvement Project Achieves 30-Minute Door-to-Needle Time Journal of Emergency Nursing
Online learning and emergency global health partnerships: a qualitative study of virtual grand rounds Emergency Medicine Journal
Pre-CT risk stratification using the D-dimer/pCO₂ ratio in D-dimer–positive emergency department patients: diagnostic accuracy study BMC Emergency Medicine
The Hidden Cost of Long Working Hours: Occupational Anxiety and Argumentativeness in Emergency Nurses Journal of Emergency Nursing
The Junior Emergency Nurses’ Psychological Experiences in Recognizing and Responding to Clinical Deterioration of Emergency Patients: A Qualitative Study Journal of Emergency Nursing
Utilisation of an emergency medical services pathway into a virtual emergency department and the impact on non-transports and patient safety Emergency Medicine Journal
Paediatrics
Application of the PECARN prediction rule for febrile infants up to 90 days of age: a multi-center study BMC Pediatrics
Assessing Outcomes of Point-of-Care Ultrasound Use in Testicular Torsion in a Pediatric Emergency Department Pediatric Emergency Care
Calcitonin Gene–Related Peptide for Identifying Pediatric Bacterial Musculoskeletal Infections – A Prospective, Multicenter Study Pediatric Emergency Care
Comparison of Adenosine Administration Utilizing a Single-Syringe Versus a Double-Syringe Method in a Simulated Pediatric Patient Pediatric Emergency Care
Comparison of Adolescent, Parent, Nurse and Physician Pain Assessment in Pediatric Emergency Departments Journal of Emergency Nursing
Early Drainage Versus Antibiotic Treatment of Dental Abscesses in the Pediatric Emergency Department Pediatric Emergency Care
Evaluating the diagnostic accuracy of point-of-care ultrasound for paediatric appendicitis: a UK multicentre observational study Archives of Disease in Childhood
Indicators of early transfusion in paediatric trauma: a retrospective analysis of 11,849 cases from the TraumaRegister DGU® Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Paediatric Fever Management Practices and Antipyretic Use Among Doctors and Nurses in Australian Emergency Departments Emergency Medicine Australasia
Prevalence of Gender Identity and Incongruence in Adolescent Patients Presenting With Positive Behavioral Health Screens to a Pediatric Emergency Department Pediatric Emergency Care
Reasons for Ordering a Computed Tomography Scan and Abnormalities Found in Pediatric Intermediate-Risk Mild Head Trauma Pediatric Emergency Care
Selective Use of Magnetic Resonance Imaging for Facial Palsy in the Pediatric Emergency Department Pediatric Emergency Care
The Implementation of an Extended Hours Child Life Therapy Service in a Paediatric Emergency Department Emergency Medicine Australasia
Ultrasound-Guided Nerve Block for Pediatric Femur Fractures – A Secondary Analysis of Needle Tip Distance Pediatric Emergency Care
Use of Ondansetron for Pediatric Gastroenteritis in the Pediatric Emergency Department – An Evaluation of the Pediatric Emergency Care Applied Research Network Registry Pediatric Emergency Care
Adults
A missed diagnosis of acute aortic syndrome is associated with ischaemic ECG changes and an initial suspicion of myocardial infarction: a retrospective observational study BMC Emergency Medicine
A Novel Approach: Ultrasound-Guided Transgluteal Sciatic Nerve Block Using D5W and Bupivacaine/Dexamethasone for Acute Sciatica in the Emergency Department The Journal of Emergency Medicine
Agreement between serum creatinine and fingerstick creatinine measurements in adult patients admitted to the emergency department BMC Emergency Medicine
Artificial intelligence versus human expertise: ECG-based detection of occlusive myocardial infarction after cardiac arrest Resuscitation
Can leukocyte count predict the presence of post-traumatic lesions on the WBCT in clinically stable severe trauma patients? A retrospective study BMC Emergency Medicine
Capillary refill time as a bedside perfusion indicator: associations with vital signs and triage acuity in the emergency department: a cross-sectional study BMC Emergency Medicine
Comparison of intubation characteristics with the McGrath video laryngoscope in adults using a stylet, bougie or no intubating aid Journal of Perioperative Practice
Cumulative Incidence of Stroke Disability and Mortality Following Emergency Department Discharge for Dizziness: A Cohort Study Annals of Emergency Medicine
Foreign body ingestion in adults: clinical challenges and outcomes in high-risk populations presenting to the emergency department European Journal of Gastroenterology and Hepatology
Orthogeriatric multidisciplinary care for hip fractures in emergency department reduces length of stay: a retrospective cohort study BMC Emergency Medicine
Outcomes and Implications of Patients Included vs Excluded for Extracorporeal Cardiopulmonary Resuscitation after Initial Activation Resuscitation Plus
Peripherally administered vasopressin initiated in the emergency department Journal of Critical Care
Prevalence, symptoms, risk factors and impact of sepsis-associated encephalopathy in emergency department patients: a case-control study BMC Emergency Medicine
Retrospective observational cohort study of patients diagnosed with sepsis: is this really sepsis? Emergency Medicine Journal
Temporal validation of the Ramathibodi Older Sepsis Score (ROSS) for predicting 28-day mortality of older sepsis patients in the emergency department BMC Emergency Medicine
The use of point-of-care-ultrasound for suspected traumatic thyroid gland rupture The Journal of Emergency Medicine
Tranexamic acid in multiply injured patients–the independent risk of thromboembolic complications with repeated dosing: retrospective analysis based on the TraumaRegister DGU® Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Zalunfiban at First Medical Contact for ST-Elevation Myocardial Infarction NEJM Evidence
Metadata
Summary author: Rebecca Howes
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash
