Emergency Evidence Updates – October 2025
Randomised Controlled Trials
Adjunctive Atorvastatin for Sepsis in the Acute Medical Unit: A Randomized Controlled Trial Acute Medicine
Intranasal Versus Subcutaneous Ketamine for the Treatment of Acute Traumatic Pain in the Emergency Department: A Randomized Clinical Trial Annals of Emergency Medicine
NICE
Head injury QS74
Other Guidance/Reports
Developing a clinical decision tool to support paramedics when assessing and managing children with minor head injury BMC Emergency Medicine
European Resuscitation Council Guidelines 2025 Ethics in Resuscitation Resuscitation
European Resuscitation Council Guidelines 2025 First Aid Resuscitation
European Resuscitation Council Guidelines 2025 System Saving Lives Resuscitation
European Resuscitation Council Guidelines 2025 Adult Basic Life Support Resuscitation
European Resuscitation Council Guidelines 2025 Executive Summary Resuscitation
European Resuscitation Council Guidelines 2025 Paediatric Life Support Resuscitation
Primary Research
Prehospital
Development and evaluation of a novel prehospital antidote service providing methylthioninium chloride (methylene blue) for sodium nitrite poisoning Emergency Medicine Journal
Impact of on-scene time interval on survival in traumatic out-of-hospital cardiac arrest Injury
Prehospital transfusion: an 8-year descriptive retrospective monocenter study BMC Emergency Medicine
Successful prehospital extracorporeal cardiopulmonary resuscitation in pediatric cardiac arrest – a case report Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
General
Beneath the Personal Protective Equipment: Perspectives on Infection Prevention and Control From Emergency Department Health Care Personnel Journal of Emergency Nursing
Evaluating the impact of AI assistance on decision-making in emergency doctors interpreting chest X-rays: a multi-reader multi-case study Emergency Medicine Journal
High ratio of plasma to red cells in contemporary resuscitation of haemorrhagic shock after trauma: a secondary analysis of the PATCH-trauma trial Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
How is same day emergency care (SDEC) being implemented across England? Emergency Medicine Journal
Low Clinical Value Pathology Tests in the Emergency Department: Audit of Urine Microbiology and Culture Use at a Large Regional Centre Emergency Medicine Australasia
Therapeutic target of high fresh frozen plasma to red blood cell ratio in severe blunt trauma Critical Care
Paediatrics
A Case of POUNCE Syndrome Requiring Suboccipital Craniectomy with a Favorable Neurological Outcome The Journal of Emergency Medicine
Application of Step-by-Step and Paediatric Emergency Care Applied Research Network (PECARN) Clinical Decision Aids in the management of young febrile infants in a UK cohort Emergency Medicine Journal
Association Between Hyperuricemia and Dehydration in Children With Acute Gastroenteritis Pediatric Emergency Care
Balanoposthitis in children: does treatment matter? The Journal of Emergency Medicine
Corrected QT Intervals in the Pediatric Emergency Department – Don’t Be Misled Pediatric Emergency Care
Decreased Lumbar Puncture Utilization Following Implementation of Febrile Infant Guidelines in a Pediatric ED Pediatric Emergency Care
Development and Implementation of the Modified Pediatric Emergency Department Overcrowding Scale in Two Large Academic Pediatric Centers Journal of Emergency Nursing
Diagnosis of late-presenting congenital diaphragmatic hernia by point-of-care ultrasound The Journal of Emergency Medicine
Distribution of Nonstandard Inflammatory and Cardiac Biomarker Levels in Children With Fever and Viral or Nonspecific Illness Pediatric Emergency Care
Optimizing Pediatric Trauma Team Performance Through Interdisciplinary Trauma Simulation and Feedback From Trauma Code Video Analysis Pediatric Emergency Care
Sketching Silence – Exploring the Use of Children’s Drawings as an Early Bullying Detection Tool Pediatric Emergency Care
Standardization of Discharge Instructions by Age for Children Presenting to the ED With Mild Traumatic Brain Injury – A Quality Improvement Project Pediatric Emergency Care
Utility of Shock Index and Pediatric Age-Adjusted Shock Index in Predicting Severe Sepsis and Septic Shock Pediatric Emergency Care
Adult
Associations Between Sex, Race/Ethnicity, and HEART Score Guideline Implementation for Cardiac Testing in the Emergency Department The Journal of Emergency Medicine
Balancing Cure and Care for Geriatric Patients With Frailty in Emergency Care: A Qualitative Study Journal of Emergency Nursing
Development and psychometric validation of a first aid health literacy assessment questionnaire for older adults BMC Emergency Medicine
Early lactate dynamics for short-term mortality in emergency department sepsis BMC Emergency Medicine
Efficacy of Adding Intravenous Saline Solution to Nonsteroidal Anti-Inflammatory Drug-Based Treatment of Acute Migraine in the Emergency Department Annals of Emergency Medicine
Impact of atypical presenting symptoms on door-to-balloon time and mortality outcomes in ST-segment elevation myocardial infarction BMC Emergency Medicine
Impact of strategies to improve flow and lower hospital admissions for low back pain in the emergency department: an interrupted time-series analysis Emergency Medicine Journal
“Is my face swollen?” – Utilizing POCUS to Diagnose Odontogenic infections The Journal of Emergency Medicine
pH-Corrected Ionised Calcium Predicts Coagulopathy After Major Trauma: A Retrospective Cohort Study Emergency Medicine Australasia
Phantom Scanning in Point-of-Care Ultrasound after Out-of-Hospital Cardiac Arrest: Impact of Clinical Presentation in a Single-Center Analysis The Journal of Emergency Medicine
Physiological scoring systems for early identification of critically ill older adults in the emergency department: a prospective observational cohort study BMC Emergency Medicine
Prognostic value of lactate-to-hemoglobin ratio in nontraumatic critically ill patients presenting to the emergency department: a retrospective cohort study BMC Emergency Medicine
Reducing time from presentation to diagnosis of scaphoid fractures with cone beam CT: a before-and-after study Emergency Medicine Journal
The association of blood transfusion and sustained return of spontaneous circulation in blunt traumatic out-of-hospital cardiac arrest Emergency Medicine Journal
The Prognostic Value of the Clinical Frailty Scale in Critically Ill Older Adult Patients in the Emergency Department The Journal of Emergency Medicine
Use of in-hospital mild traumatic brain injury symptom checklist within 24 hours of injury to predict 3-month symptom outcome The Journal of Emergency Medicine
Weather and Hip Fractures: A Nine-Year Study across England and Wales Injury
Metadata
Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash
