Category: Evidence-based Medicine

Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock ANDROMEDA SHOCK 2 Investigators @ShockAndromeda2. JAMA 2025. doi:10.1001/jama.2025.20402 Clinical Question In adult patients with early septic shock, does a personalised haemodynamic resuscitation protocol targeting capillary refill time (CRT) normalisation improve outcomes compared to usual care? Background In septic shock, the pathophysiological mechanisms contributing to the development of a shocked […]