Emergency Evidence Updates – September 2025

Randomised Controlled Trials

Effect of a portable therapeutic baby nest designed for neonates on physiological parameters, comfort and pain levels during venous blood sampling: a randomised controlled trial  Emergency Medicine Journal

Effect of Distracting Methods on Procedure-Related Fear, Anxiety, and Pain During Intramuscular Injection: A Randomized Controlled Trial  Journal of Emergency Nursing

Factors in the Initial Resuscitation of Patients With Severe Trauma – The FiiRST-2 Randomized Clinical Trial  JAMA Network Open

Health Services and Economic Impacts of the Limit of Detection in Emergency Department (LEGEND) Rule-Out Strategy in Australian Emergency Departments: A Stepped-Wedge Cluster Randomised Trial  Emergency Medicine Australasia

Non-pharmacological de-escalation techniques used to manage acute severe behavioural disturbance in children and adolescents presenting to emergency departments: secondary analysis of a randomised controlled trial  Archives of Disease in Childhood

Optimal Dose of Intranasal Midazolam for Procedural Sedation in Children – A Randomized Clinical Trial  JAMA Pediatrics

Peripheral Perfusion vs Standard Management in Sepsis/Septic Shock: A Prospective Randomized ED Study  The American Journal of Emergency Medicine

The Effectiveness of Intranasal Ketamine on Intramuscular Ketamine Injection Pain Among Children in the Emergency Department, a Randomized, Controlled Trial  Pediatric Emergency Care

NICE

Pneumonia: diagnosis and management NG250

Pneumonia: diagnosis and management QS110

Suspected acute respiratory infection in over 16s: assessment at first presentation and initial management NG237

Other Guidance/Reports

PIER

Recommendations for the Prevention and Management of Oral Complication in Children and Young People with Cancer (CCLG)

CCLG Guideline for Vaccinations for Paediatric Patients Treated with Standard Dose Chemotherapy and Haemopoeitic Stem Cell Transplants​​

Re-vaccination Schedule for Patients Beginning 3 months After Completion of Standard Dose Chemotherapy

Primary Research

Prehospital

Admission Hypothermia in Trauma Patients Undergoing Prehospital Tracheal Intubation: 15-Year Review of a Level-1 Trauma Center  Prehospital Emergency Care

Association of prehospital pupillary diameter with return of spontaneous circulation and neurological outcome after out-of-hospital cardiac arrest: A multicenter retrospective analysis  Resuscitation Plus

‘Every day was a learning curve’: implementing COVID-19 triage protocols in UK ambulance services—a qualitative study of staff experiences  Emergency Medicine Journal

Implementing prehospital invasive arterial blood pressure monitoring in critically ill patients—a prospective observational first year analysis  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Pre-hospital THRIVE score predicts the thrombolysis in cerebral infarction outcome post endovascular thrombectomy: an emergency medical service study  BMC Emergency Medicine

The relationship between cardiopulmonary resuscitation duration and prognosis in patients with out-of-hospital cardiac arrest due to asphyxiation  Resuscitation

 

General

A Pilot Study Using Casino Shifts to Improve Sleep for Emergency Medicine Fellows Working Night Shifts  Pediatric Emergency Care

Building a psychiatric boarding toolkit: an emergency nursing perspective on a collaborative approach to care  The Journal of Emergency Medicine

Detecting acute ischemic lesions using mobile, low-field MRI in TIA and minor stroke in the emergency room  International Journal of Stroke

Effectiveness of a Smartwatch-Based Feedback System in Improving Cardiopulmonary Resuscitation Quality: A Simulation Study  Resuscitation Plus

Emergency physicians’ perspectives on integrating physiotherapists into emergency departments: a national survey from France  Emergency Medicine Journal

Foley Tubing as a Luer Adapter for Thoracic Lavage in Severe Hypothermia  The Journal of Emergency Medicine

Machine learning model to predict mortality in patients with skin and soft tissue infection in emergency department  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Perceived Relationships Between Emergency Department Staffing Patterns and Missed Care, Missed Decompensation, and Delays in Care  Journal of Emergency Nursing

Performance of ChatGPT, Gemini and DeepSeek for non-critical triage support using real-world conversations in emergency department  BMC Emergency Medicine

The Impact of Interim Care Plans for Direct Inpatient Admissions on Emergency Department Length of Stay: A Retrospective Single-Site Matched-Cohort Study  Emergency Medicine Australasia

 

Paediatrics

Association of Suicide Risk Factors and Subsequent Pediatric Emergency Department Mental Health Visits  Pediatric Emergency Care

Characteristics of Young Children Presenting to the Emergency Department for Psychiatric Evaluation  The Journal of Emergency Medicine

Child death in the emergency department: experience from a 10-year retrospective review  Archives of Disease in Childhood

Clinical Pathway Revision Increases Amoxicillin Monotherapy and 5-Day Durations of Therapy for Pediatric Community-Acquired Pneumonia in the Emergency Department and Urgent Care: A Quality Improvement Initiative  Annals of Emergency Medicine

Experiences of Pediatricians Caring for Children and Adolescents With Mental Health Needs in the Emergency Department, 2022  Pediatric Emergency Care

Gonorrhea and Chlamydia Screening for Adolescents and Young Adults in Emergency Departments  JAMA Pediatrics

Herpes simplex virus disease in infants younger than 90 days: a British Paediatric Surveillance Unit study  Archives of Disease in Childhood

Hospital Readmission Among Survivors of Pediatric Out-of-Hospital Cardiac Arrest: An Analysis of the Nationwide Readmissions Database  Resuscitation

Improving Antibiotic Administration Time in At-Risk Pediatric Populations: A Quality Improvement Project  Journal of Emergency Nursing

Measured Serum Osmolality as a Severity Marker of Pediatric Hyperglycemic Crises  Pediatric Emergency Care

Measuring Ventilation in Pediatric Simulations Using a Novel Adjustable Bag-Valve-Mask Resuscitator: A Comparative Study with the Butterfly BVM and the Traditional Ambu Bag  Resuscitation Plus

Not so FAST! Review of Adolescent Point-of-Care Ultrasound Reveals Splenic Mass Requiring Splenectomy  Pediatric Emergency Care

Opioid Timeliness in the Emergency Department and Hospitalizations for Acute Sickle Cell Pain  JAMA Pediatrics

Optimizing CPR performance: the role of body composition and ergonomic positioning  BMC Emergency Medicine

Point-of-Care Ultrasound Evaluation of Biliary Atresia in the Pediatric Emergency Department  Pediatric Emergency Care

Predicting Pediatric Cardiac Arrest Outcomes Using Early Quantitative EEG  Resuscitation

Resource Utilization for Brief Resolved Unexplained Events in a Pediatric and General Emergency Department   Pediatric Emergency Care

Sentinel Injuries in Emergency Departments and Subsequent Serious Injury in Children  Annals of Emergency Medicine

Tissue Adhesive as an Alternative to Sutures in Pediatric Eye Emergency – A Clinical Prospective Comparative Cohort Study  Pediatric Emergency Care

Validating the PECARN rule to identify febrile infants at low risk of serious bacterial infections: an international validation study  Archives of Disease in Childhood

 

Adults

Accuracy of Published Screening Tools for Large Vessel Occlusion in Patients With Suspected Acute Ischemic Stroke: A Prospective Cohort Study  Annals of Emergency Medicine

Antibiotic Therapy for Pyelonephritis in the Emergency Department  Emergency Medicine Australasia

Association of Troponin Elevation with Cardiovascular Event in Stable Supraventricular Tachycardia in the Emergency Department  The Journal of Emergency Medicine

Computed Tomography Head Ordering Practices in Residential Aged Care Facility Residents Presenting to Emergency Department After an Unwitnessed Fall  Emergency Medicine Australasia

Horsing Around: A Retrospective Study of Equestrian Related Eye Injuries in the Emergency Department  The Journal of Emergency Medicine

Is our understanding of Hyperosmolar Hyperglycemic State accurate?  The Journal of Emergency Medicine

Patients and hospital staff perceive diverting patients from the emergency department to physiotherapy outpatients as safe and effective: a qualitative descriptive study  Physiotherapy Theory and Practice

Recall incidence After Procedural Sedation with Propofol in Emergency Departments  The Journal of Emergency Medicine

Serious Cardiac Outcomes and Physician Estimation of Risk in Emergency Department Patients With Presyncope Versus Syncope  Annals of Emergency Medicine

The stiff leg sign in acute thigh & gluteal compartment syndrome: A case report  Trauma

Metadata

Summary author: Rebecca Howes
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash

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