Emergency Evidence Updates – September 2026

Randomised Controlled Trials

Effect of Intravenous Pantoprazole on Clinical Outcomes in Pediatric Acute Gastroenteritis: A Placebo-Controlled RCT  Pediatric Emergency Care

Effects of Different Nasal Irrigation Methods on Pain, Crying and Procedure Times in Nasal Congestion in Infants: A Randomized Controlled Trial  Journal of Emergency Nursing

Intraosseous versus intravenous access in adult out-of-hospital cardiac arrest: a Bayesian secondary analysis of the PARAMEDIC-3 randomised controlled trial  Resuscitation

Intranasal lidocaine spray during nasogastric tube placement: a randomized, double-blind, placebo-controlled trial  BMC Emergency Medicine

Telehealth Treatment of Anxiety in Patients With Low-Risk Chest Pain in the Emergency Department – The PACER Randomized Clinical Trial  JAMA Internal Medicine

 

NICE

Suspected sepsis in people aged 16 or over: recognition, assessment and early management NG253

 

Other Guidance/Reports

Defining the concept of Mental Dysregulation in patients requiring ambulance and Emergency Department care; results of an international modified Delphi study  BMC Emergency Medicine

Paediatric Procedural Sedation and Analgesia in Emergency Departments: A Delphi Consensus Study  Emergency Medicine Australasia

 

Cochrane

Factors that impact on healthcare workers’ adherence with infection prevention and control (IPC) guidelines for COVID‐19: a qualitative evidence synthesis

 

Primary Research

Prehospital

Rescue-breathing versus chest compression-only bystander cardiopulmonary resuscitation in non-cardiac out-of-hospital cardiac arrest: a nationwide retrospective cohort study   Resuscitation

When prehospital resuscitation attempts are unsuccessful: care for the relatives following termination of treatment in out-of-hospital cardiac arrest  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

 

General

Artificial Intelligence Triage of Urgent Versus Non-Urgent CT Brain Findings to Support Expedited Emergency Department Disposition: A Retrospective Validation Study  Emergency Medicine Australasia

Deaf-led Deaf Awareness Training in the Emergency Department: A Pre-Post Evaluation of Staff Knowledge, Confidence, and Communication Preparedness  Journal of Emergency Nursing

Discovery of eight stable subgroups of sepsis in the emergency department with consensus clustering  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Embedded Low-Acuity Pathway in the Emergency Department: An Alternative to Stand-Alone Urgent Care Services  Emergency Medicine Australasia

How Thriving at Work Alleviates Alarm Fatigue: The Mediating Effect of Problem-Solving Ability in Emergency Nurses  Journal of Emergency Nursing

Implementation of a Structured Hot Debrief Tool in a Metropolitan ED: A Quality Improvement Study  Emergency Medicine Australasia

Incremental predictive value of the Nurse Intuition Patient Deterioration Scale added to MEWS in an emergency observation unit: a retrospective validation and before-after analysis  BMC Emergency Medicine

Instituting Nurse-Led Delirium Screening in a Windowless Emergency Department-Adjacent Observation Unit: Findings From a Quality Improvement Project  Journal of Emergency Nursing

Will Artificial Intelligence Replace Me? Automation Susceptibility of Emergency Physician Tasks  Annals of Emergency Medicine

 

Paediatric

A Badge-Sized Cognitive Aid and Pediatric Point-of-Care Ultrasound Integration in the Emergency Department  Pediatric Emergency Care

Clinical and Laboratory Findings When Pediatric Male Sexual Assault Survivors Present to the Emergency Department  Pediatric Emergency Care

Diagnostic Utility of the Albumin-to-Globulin Ratio for Kawasaki Disease in Children Presenting to the Emergency Department  Pediatric Emergency Care

Factors Influencing Caregiver Anxiety in the Pediatric Emergency Department  Pediatric Emergency Care

Intranasal Dexmedetomidine for Paediatric Procedural Sedation in the Emergency Department: A Single-Centre Retrospective Observational Cohort Study  Emergency Medicine Australasia

Risk Factors for Undertriage of Children Presenting to a Pediatric Emergency Department With Abdominal Pain  Pediatric Emergency Care

The Impact of Tablet-Based Screening on Trichomonas Testing in the Pediatric Emergency Department  Pediatric Emergency Care

 

Adult

Development and validation of a model to predict post-intubation hypotension in the emergency department: a retrospective study  BMC Emergency Medicine

Diagnostic performance of procalcitonin for differentiating infectious and non-infectious conditions in emergency department patients with reduced kidney function  BMC Emergency Medicine

Efficacy and Safety of Ventilator Assisted Preoxygenation for Intubation in Two Australian Emergency Departments: A Retrospective Cohort Study  Emergency Medicine Australasia

 

Metadata

Summary author: Rebecca Howes
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash