Ferrer
In patients with severe sepsis or septic shock, is the timing of first administration of antibiotics associated with the in-hospital mortality rate?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
In patients with severe sepsis or septic shock, is the timing of first administration of antibiotics associated with the in-hospital mortality rate?
Continue reading »In adult patients undergoing mechanical ventilation, does a strategy involving no continuous sedation, compared to a strategy of continuous sedation by infusion with a daily interruption, reduce the number of days of mechanical ventilation in the first 4 weeks?
Continue reading »In critically ill adults that are expected to be in Intensive Care for 3 days or more, does intensively controlled blood glucose compared to conventionally controlled blood glucose reduce mortality at 90 days?
Continue reading »In adult patients with severe septic shock, does hydrocortisone versus placebo reduce mortality at 28 days?
Continue reading »In high-risk patients undergoing gastrointestinal surgery, does a cardiac output-guided haemodynamic therapy algorithm compared to clinician-guided standard therapy reduce death and major morbidity within 30 days?
Continue reading »In patients with Acute Lung Injury (ALI) or Acute Respiratory Distress Syndrome (ARDS), does ventilation with lower tidal volumes compared with traditional higher tidal volumes reduce death or ventilator-free days?
Continue reading »In medical patients who are intubated, mechanically ventilated and sedated by a continuous infusion of drugs, do daily sedative interruptions reduce the duration of mechanical ventilation or length of stay?
Continue reading »In adults who suffer cardiac arrest due to ventricular fibrillation, does mild hypothermia compared with standard normothermia improve neurological outcome at 6 months?
Continue reading »In patients with early ARDS, does continuous methylprednisolone compared to placebo reduce lung injury scores within 7 days?
Continue reading »In patients who are mechanically ventilated and sedated with opioids and / or benzodiazepines, do daily sedative interruptions reduce the duration until extubation?
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