BALANCE
In patients undergoing major surgery who are at high risk of complications, does light anaesthesia (BIS 50) compared with deep anaesthesia (BIS 35) improve survival at 1-year?
Continue reading »Author: Duncan Chambler
Subira
In patients weaning from mechanical ventilation, does a spontaneous breathing trial (SBT) with pressure support (PS) for 30 minutes vs a SBT with T-piece for 2 hours differ in the rate of successful liberation from mechanical ventilation (MV)?
Continue reading »SoM
Contact precautions in single-bed or multiple-bed rooms for patients with extended-spectrum Beta-lactamase-producing enterobacteriaceae in Dutch hospitals Kluytmans-van den Bergh. Lancet Infectious Diseases 2019; Published online 23rd August 2019. doi: 10.1016/S1473-3099(19)30262-2. Clinical Question In non-ICU, non-haematology patients that have been identified as carriers of extended-spectrum beta-lactamase-producing enterobacteriaceae (ESBLs), is a strategy of contact precautions in a multiple-bed room compared to contact […]
Continue reading »DRAIN
In adults with decompensated heart failure who are at high-risk of diuretic resistance, does furosemide administered by infusion compared to intermittent bolus increase the incidence of freedom from congestion at 72 hours?
Continue reading »AVB-TIPS
In patients with cirrhosis and acute variceal bleeding, does early transjugular intrahepatic portosystemic shunt (TIPS) compared to standard care increase transplant-free survival?
Continue reading »REDUCE Haloperidol
In critically ill adults, does haloperidol 1 mg or haloperidol 2 mg given three times a day compared to placebo reduce mortality?
Continue reading »TBL at WICS Summer 2019
TBL at Wessex Intensive Care Society meeting 2019 #WICS19 It’s a pleasure to be speaking at WICS 2019. I will be producing notes here to support my talk later today. This will include a narrative of my slides, a little more depth of content and links to all the trials. In short, here are my 6 key statements: Video-laryngoscopy is […]
Continue reading »ICON
In critically ill adults that survive their acute illness, what is the incidence of depression, anxiety and post-traumatic stress disorder?
Continue reading »BREATHE
In adult patients on invasive mechanical ventilation who are difficult to wean, does extubation and weaning on non-invasive ventilation compared to weaning on invasive ventilation reduce the time until liberation from mechanical ventilation?
Continue reading »IMPACT
In adult patients at risk of nausea and vomiting during surgery, do multiple antiemetic interventions compared to single antiemetic interventions or no intervention reduce nausea and vomiting?
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