THAPCA-OH
In children suffering an out-of-hospital cardiac arrest, does hypothermia compared to normothermia increase survival with a good neurobehavioural outcome?
Continue reading »Author: Duncan Chambler
PermiT
In critically ill adults, does restriction of non-protein calories (permissive underfeeding) compared to standard feeding reduce mortality at 90 days?
Continue reading »Loubani
In patients who are administered vasopressor medication intravenously, what are the published reports on local tissue injury and extravasation?
Continue reading »EUSOS
What is the clinical outcome of patients after major non-cardiac surgery in Europe?
Continue reading »Lyon
In pre-hospital trauma patients undergoing rapid sequence intubation (RSI), does fentanyl-ketamine-rocuronium induction compared to etomidate-suxamethonium induction affect intubation success or haemodynamic responses to laryngoscopy?
Continue reading »STOPAH
In adult patients with alcoholic hepatitis, does prednisolone and / or pentoxifylline compared to placebo reduce mortality?
Continue reading »Gu
In adult patients with sepsis, severe sepsis or septic shock, is a single dose of etomidate for induction of anaesthesia, compared with any other induction, associated with a difference in mortality?
Continue reading »TITRe2
In adults undergoing cardiac surgery, does a restrictive transfusion strategy (Hb > 75 g/l) compared to a liberal transfusion strategy (Hb > 90 g/l) lead to fewer infections and ischaemic events within 3 months?
Continue reading »Determann
In mechanically ventilated patients without acute lung injury or acute respiratory distress (ALI/ARDS), does lower tidal volume ventilation at 6 ml/kg (Vt-low), compared to conventional tidal volume ventilation at 10 ml/kg (Vt-high), reduce cytokine levels associated with lung injury?
Continue reading »VITdAL-ICU
In critically ill patients with low serum vitamin D levels, does high-dose vitamin D supplementation compared with placebo reduce hospital length of stay?
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