Critical Care Evidence Updates – August 2022
Randomised Controlled Trials
Acetazolamide in Acute Decompensated Heart Failure with Volume Overload NEJM
An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis (DEFINE): A Phase Ib/IIa Randomised Controlled Trial American Journal of Respiratory and Critical Care Medicine
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest NEJM
Continuous intra-arterial versus intermittent oscillometric arterial pressure monitoring and hypotension during induction of anaesthesia: the AWAKE randomised trial British Journal of Anaesthesia
Driving pressure-guided ventilation and postoperative pulmonary complications in thoracic surgery: a multicentre randomised clinical trial British Journal of Anaesthesia
Effect of high versus low dose of dexamethasone on clinical worsening in patients hospitalised with moderate or severe COVID-19 pneumonia: an open-label, randomised clinical trial European Respiratory Journal
Effects of mean arterial pressure target on mottling and arterial lactate normalization in patients with septic shock: a post hoc analysis of the SEPSISPAM randomized trial Annals of Intensive Care
Oxygen Targets in Comatose Survivors of Cardiac Arrest NEJM
Reduction in transfer of micro-organisms between patients and staff using short-sleeved gowns and hand/arm hygiene in intensive care during the COVID-19 pandemic: A simulation-based randomised trial Journal of the Intensive Care Society
The Use of IV Vasoactive Intestinal Peptide (Aviptadil) in Patients With Critical COVID-19 Respiratory Failure: Results of a 60-Day Randomized Controlled Trial Critical Care Medicine
Timing of Exposure to ICU Diaries and Its Impact on Mental Health, Memories, and Quality of Life: A Double-Blind Randomized Control Trial Critical Care Explorations
NICE
SecurAcath for securing percutaneous catheters MTG34
Superficial venous arterialisation for chronic limb threatening ischaemia IPG736
Other Guidance/Reports
Clinical sepsis phenotypes in critically ill COVID-19 patients Critical Care
ESC Congress 2022 Guidelines European Heart Journal
Interviews with primary care physicians identify unmet transition needs after ICU Critical Care
Management of Decompensated Cirrhosis in the Surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document Trauma Surgery & Acute Care Open
New drugs for acute kidney injury Intensive Care Medicine
Preventing pressure injuries among patients in the intensive care unit: insights gained
Intensive Care Medicine
Update June 2022: management of hospitalised adults with coronavirus disease 2019 (COVID-19): a European Respiratory Society living guideline European Respiratory Journal
Update on vitamin C administration in critical illness Current Opinion in Critical Care
Cochrane
Primary Research
A Care Step Pathway for the Diagnosis and Treatment of COVID-19–Associated Invasive Fungal Infections in the Intensive Care Unit Critical Care Nurse
A Multiple Baseline Trial of an Electronic ICU Discharge Summary Tool for Improving Quality of Care Critical Care Medicine
A thematic analysis of staff perspectives on the impact of a mental health nurse (RMN) in a critical care unit Journal of the Intensive Care Society
A stratification strategy to predict secondary infection in critical illness-induced immune dysfunction: the REALIST score Annals of Intensive Care
Acute bilateral parotid swelling upon laryngeal mask airway insertion: A case report Anaesthesia and Intensive Care
Association between histological diaphragm atrophy and ultrasound diaphragm expiratory thickness in ventilated patients Journal of Intensive Care
Bebtelovimab-Induced Bradycardia Leading to Cardiac Arrest Critical Care Explorations
Care practices for patients requiring mechanical ventilation more than seven days in Swedish intensive care units: A national survey Intensive and Critical Care Nursing
Co-infection and ICU-acquired infection in COVID-19 ICU patients: a secondary analysis of the UNITE-COVID data set Critical Care
Comparison of different clinical risk scores to predict long-term survival and neurological outcome in adults after cardiac arrest: results from a prospective cohort study Annals of Intensive Care
Development and Implementation of an Ultrasound-Guided Peripheral Intravenous Catheter Education Program for Critical Care Nurses Dimensions of Critical Care Nursing
Duration of resuscitation and long-term outcome after in-hospital cardiac arrest: A nationwide observational study Resuscitation
Early prediction of hospital outcomes in patients tracheostomized for complex mechanical ventilation weaning Annals of Intensive Care
Early steroids and ventilator-associated pneumonia in COVID-19-related ARDS Critical Care
Ecological effects of selective oral decontamination on multidrug-resistance bacteria acquired in the intensive care unit: a case–control study over 5 years Intensive Care Medicine
Effects of Ketamine Infusion on Breathing and Encephalography in Spontaneously Breathing ICU Patients Journal of Intensive Care Medicine
Elimination of Herpes Simplex Virus-2 and Epstein-Barr Virus With Seraph 100 Microbind Affinity Blood Filter and Therapeutic Plasma Exchange: An Explorative Study in a Patient With Acute Liver Failure Critical Care Explorations
Exploration of a rapid response team model of care: A descriptive dual methods study Intensive and Critical Care Nursing
Family support in intensive care units during COVID-19 visit ban: A multinational Delphi Study during first COVID-19 wave Intensive and Critical Care Nursing
How do intensive care clinicians ensure culturally sensitive care for family members at the end of life? A retrospective descriptive study Intensive and Critical Care Nursing
Impact of Family Presence on Delirium in Critically Ill Patients: A Retrospective Cohort Study Critical Care Medicine
Impact of Macintosh blade size on endotracheal intubation success in intensive care units: a retrospective multicenter observational MacSize-ICU study Intensive Care Medicine
In-Hospital Depressed Level of Consciousness and Long-Term Functional Outcomes in ICU Survivors Critical Care Medicine
Kinetics of capillary refill time after fluid challenge Annals of Intensive Care
Low-dose intravenous plus inhaled versus intravenous polymyxin B for the treatment of extensive drug-resistant Gram-negative ventilator-associated pneumonia in the critical illnesses: a multi-center matched case–control study Annals of Intensive Care
Management and outcomes of pregnant women admitted to intensive care unit for severe pneumonia related to SARS-CoV-2 infection: the multicenter and international COVIDPREG study Intensive Care Medicine
Mental health-related quality of life is related to delirium in intensive care patients Intensive Care Medicine
Mental well-being of ICU nurses after the second surge of the COVID-19 pandemic: A cross-sectional and longitudinal study Intensive and Critical Care Nursing
Modulation of the Association Between Age and Death by Risk Factor Burden in Critically Ill Patients With COVID-19 Critical Care Explorations
Multisystem Inflammatory Syndrome in Adults (MIS-A) After COVID-19 Infection and Recent Vaccination with Recombinant Adenoviral Vector Encoding the Spike Protein Antigen of SARS-CoV-2 (ChAdOx1 nCoV-19, Vaxzevria) Journal of Intensive Care Medicine
Muscular myostatin gene expression and plasma concentrations are decreased in critically ill patients Critical Care
One Year Post-Discharge Outcomes After Implementation of an ICU Early Mobility Protocol Dimensions of Critical Care Nursing
Optimal bispectral index level of sedation and cerebral oximetry in traumatic brain injury: a non-invasive individualized approach in critical care? Intensive Care Medicine Experimental
Optimization of central venous pressure during the perioperative period is associated with improved prognosis of high-risk operation patients Journal of Intensive Medicine
Outcomes and Prognostic Factors of Pulmonary Hypertension Patients Undergoing Emergent Endotracheal Intubation Journal of Intensive Care Medicine
Physiologic responses to exercise in survivors of critical illness: an exploratory pilot study Intensive Care Medicine Experimental
Plasma volume expansion reveals hidden metabolic acidosis in patients with diabetic ketoacidosis Intensive Care Medicine Experimental
Poor long-term recovery after critical COVID-19 during 12 months longitudinal follow-up Intensive and Critical Care Nursing
Practical Strategies Related to the Application of Balloon Tamponade Therapy in Acute Variceal Bleeding Critical Care Explorations
Preoperative cardiopulmonary exercise testing improves risk assessment of morbidity and length of stay following cytoreductive surgery with hyperthermic intraperitoneal chemotherapy Anaesthesia and Intensive Care
Psychological Attachment Orientation and Long-Term Posttraumatic Stress Symptoms Among Family Members of ICU Patients Critical Care Explorations
Psychological distress and morbidity of family members experiencing virtual visiting in intensive care during COVID-19: an observational cohort study Intensive Care Medicine
Strategies for lung- and diaphragm-protective ventilation in acute hypoxemic respiratory failure: a physiological trial Critical Care
Stress Hyperphenylalaninemia Is Associated With Mortality in Cardiac ICU: Clinical Factors, Genetic Variants, and Pteridines Critical Care Medicine
The Chronological Demographics of Ventricular-Arterial Decoupling in Patients with Sepsis and Septic Shock: A Prospective Observational Study Journal of Intensive Care Medicine
The Efficacy of Albumin Dialysis in the Treatment of Severe Cholestatic Drug-Induced Liver Injury Critical Care Explorations
The lived experience by patients and family members of extracorporeal membrane oxygenation: A qualitative study Intensive and Critical Care Nursing
The use of ICU resources in CAR-T cell recipients: a hospital-wide study Annals of Intensive Care
Time-varying intensity of oxygen exposure is associated with mortality in critically ill patients with mechanical ventilation Critical Care
Trauma-induced coagulopathy Intensive Care Medicine
Visual and auditory stimulation for patients in the intensive care unit: A mixed-method study Intensive and Critical Care Nursing
Metadata
Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash
