Critical Care Evidence Updates – August 2024
Randomised Controlled Trials
Beta-Blocker Interruption or Continuation after Myocardial Infarction NEJM
Continuation vs Discontinuation of Renin-Angiotensin System Inhibitors Before Major Noncardiac Surgery The Stop-or-Not Randomized Clinical Trial JAMA
Efficacy and Safety of Early Treatment with Glibenclamide in Patients with Aneurysmal Subarachnoid Hemorrhage: A Randomized Controlled Trial Neurocritical Care
Long-term effects of flexible visitation in the intensive care unit on family members’ mental health: 12-month results from a randomized clinical trial Intensive Care Medicine
Lower-Dosage Acute Peritoneal Dialysis versus Acute Intermittent Hemodialysis in Acute Kidney Injury A Randomized Controlled Trial CJASN
Nasal high flow or noninvasive ventilation? navigating hypercapnic COPD exacerbation treatment: A randomized noninferiority clinical trial Respiratory Medicine
Prolonged vs shorter awake prone positioning for COVID-19 patients with acute respiratory failure: a multicenter, randomised controlled trial Intensive Care Medicine
Suvorexant for Reduction of Delirium in Older Adults After Hospitalization – A Randomized Clinical Trial JAMA Network Open
NICE
Adrenal insufficiency: identification and management NG243
Other Guidance/Reports
2024 European Society of Hypertension clinical practice guidelines for the management of arterial hypertension European Journal of Internal Medicine
AARC Clinical Practice Guideline: Patient-Ventilator Assessment Respiratory Care
Anesthesiologists ultrasound-guided regional anesthesia core curriculum: a Delphi consensus from Italian regional anesthesia experts Journal of Anesthesia, Analgesia and Critical Care
Definition and management of right ventricular injury in adult patients receiving extracorporeal membrane oxygenation for respiratory support using the Delphi method: a PRORVnet study. Expert position statements Intensive Care Medicine
ESPEN practical guideline on clinical nutrition in hospitalized patients with acute or chronic kidney disease Clinical Nutrition
Expert perspectives on ECCO2R for acute hypoxemic respiratory failure: consensus of a 2022 European roundtable meeting Annals of Intensive Care
Guideline on positioning and early mobilisation in the critically ill by an expert panel Intensive Care Medicine
International consensus definitions for infection-triggered encephalopathy syndromes Developmental Medicine & Child Neurology
Intraoperative somatosensory evoked potential (SEP) monitoring: an updated position statement by the American Society of Neurophysiological Monitoring Journal of Clinical Monitoring and Computing
Ketamine analgo-sedation for mechanically ventilated critically ill adults: A rapid practice guideline from the Saudi Critical Care Society and the Scandinavian Society of Anesthesiology and Intensive Care Medicine Acta Anaesthesiologica Scandinavica
Obesity and cardiovascular disease: an ESC clinical consensus statement European Heart Journal
Recommendations for clinical trial design in acute kidney injury from the 31st acute disease quality initiative consensus conference. A consensus statement Intensive Care Medicine
The use of angiotensin II for the management of distributive shock: expert consensus statements Journal of Anesthesia, Analgesia and Critical Care
Cochrane
Primary Research
A modified screening protocol for ARDS in patients with respiratory support based on SpO2 and FiO2: A single-center prospective, observational study Journal of Intensive Medicine
A pilot feasibility study comparing large language models in extracting key information from ICU patient text records from an Irish population Intensive Care Medicine Experimental
A retrospective registry-based study into the proportion of patients admitted to intensive care who have anaphylaxis as a principal diagnosis and their outcomes in Australia and New Zealand Critical Care and Resuscitation
Alteration in early resting‑state functional MRI activity in comatose survivors of cardiac arrest: a prospective cohort study Critical Care
Association of norepinephrine with pressure ulcer development in critically ill patients with COVID-19-related acute respiratory distress syndrome: A dose–response analysis Intensive and Critical Care
Changes in nitric oxide inhibitors and mortality in critically ill patients: a cohort study Annals of Intensive Care
Clinical phenotyping uncovers heterogeneous associations between corticosteroid treatment and survival in critically ill COVID-19 patients Intensive Care Medicine
Comparison of Tenecteplase Versus Alteplase for the Treatment of Pulmonary Embolism and Cardiac Arrest with Suspected Pulmonary Embolism Journal of Intensive Care Medicine
Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation Intensive Care Medicine
Conservative Treatment of Mesenteric and Hepatic Portal Venous Gas Caused by Gut-Derived Infection After Ileostomy: A Case Report Critical Care Nurse
Contribution of intrapulmonary shunt to the pathogenesis of profound hypoxaemia in viral infection: a mechanistic discussion with an illustrative case Journal of the Intensive Care Society
Correlation and concordance of carotid Doppler ultrasound and echocardiography with invasive cardiac output measurement in critically ill patients Intensive Care Medicine Experimental
Derivation and external validation of predictive models for invasive mechanical ventilation in intensive care unit patients with COVID-19 Annals of Intensive Care
Dexmedetomidine Improves Microcirculatory Alterations in Patients With Initial Resuscitated Septic Shock Journal of Intensive Care Medicine
Droxidopa for Vasopressor Weaning in Critically Ill Patients with Persistent Hypotension: A Multicenter, Retrospective, Single-Arm Observational Study Journal of Intensive Care Medicine
Early reapplication of prone position during venovenous ECMO for acute respiratory distress syndrome: a prospective observational study and propensity-matched analysis Annals of Intensive Care
Emergency Department Triage, Transfer Times, and Hospital Mortality of Patients Admitted to the ICU: A Retrospective Replication and Continuation Study Critical Care Medicine
Evaluating the Appropriateness, Consistency, and Readability of ChatGPT in Critical Care Recommendations Journal of Intensive Care Medicine
Eye tracking during a simulated start of shift safety check: An observational analysis of gaze behavior of critical care nurses Journal of the Intensive Care Society
Factors associated with cancer treatment resumption after ICU stay in patients with solid tumors Annals of Intensive Care
Fluid boluses and infusions in the early phase of resuscitation from septic shock and sepsis-induced hypotension: a retrospective report and outcome analysis from a tertiary hospital Annals of Intensive Care
ICU-Electroencephalogram Unit Improves Outcome in Status Epilepticus Patients: A Retrospective Before-After Study Critical Care Medicine
Immunomodulators in patients receiving extracorporeal membrane oxygenation for COVID-19: a propensity-score adjusted analysis of the ELSO registry Annals of Intensive Care
Impact of Hemoglobin Levels on Composite Cardiac Arrest or Stroke Outcome in Patients With Respiratory Failure Due to COVID-19 Critical Care Explorations
Incorporating Patient Values in Large Language Model Recommendations for Surrogate and Proxy Decisions Critical Care Explorations
“It’s all about setting the stage.” The nurse facilitator trial: perceived outcomes and implementation issues. A qualitative study among ICU clinicians and nurse facilitators Intensive Care Medicine
Long-term survival comparison of patients admitted to the intensive care unit following in-hospital cardiac arrest in perioperative and ward settings. A multicentre retrospective cohort study Intensive Care Medicine
Machine Learning Tools for Acute Respiratory Distress Syndrome Detection and Prediction Critical Care Medicine
Moderate IV Fluid Resuscitation Is Associated With Decreased Sepsis Mortality Critical Care Medicine
Modes of administration of nitric oxide devices and ventilators flow-by impact the delivery of pre-determined concentrations Annals of Intensive Care
Neuroprognostication, withdrawal of care and long-term outcomes after cardiopulmonary resuscitation Current Opinion in Critical Care
Nociception level index variations in ICU: curarized vs non-curarized patients — a pilot study Journal of Anesthesia, Analgesia and Critical Care
Nurse Practitioner and Physician Assistant-led Cardiovascular Surgery Postoperative Intensive Care Unit Staffing Model Journal of Intensive Care Medicine
Pericardiocentesis, Chest Tube Insertion, and Needle Thoracostomy During Resuscitation of Nontraumatic Adult In-Hospital Cardiac Arrest: A Retrospective Cohort Study Critical Care Explorations
Phenotyping COVID-19 respiratory failure in spontaneously breathing patients with AI on lung CT-scan Critical Care
Point-of-care creatinine vs. central laboratory creatinine in the critically ill Critical Care and Resuscitation
Post-discharge functional outcomes in older patients with sepsis Critical Care
Reducing Central Line–Associated Bloodstream Infections With a Multipronged Nurse-Driven Approach Critical Care Nurse
Research report: Management of dysphagia using pharyngeal electrical stimulation in the general intensive care population – A service development Journal of the Intensive Care Society
Standard versus individualised positive end-expiratory pressure (PEEP) compared by electrical impedance tomography in neurocritical care: a pilot prospective single centre study Intensive Care Medicine Experimental
Stroke Volume and Stroke Volume Variation, but not Cardiac Index Is Associated With Survival of Majorly Burned Patients in Early Burn Shock Journal of Intensive Care Medicine
The Impact of Delayed Transition From Noninvasive to Invasive Mechanical Ventilation on Hospital Mortality in Immunocompromised Patients With Sepsis Critical Care Medicine
The use of echocardiography in the management of shock in critical care: a prospective, multi-centre, observational study Intensive Care Medicine
Urine Output and Development of Acute Kidney Injury in Sepsis: A Multicenter Observational Study Journal of Intensive Care Medicine
Validating quantitative pupillometry thresholds for neuroprognostication after out-of-hospital cardiac arrest. A predefined substudy of the Blood Pressure and Oxygenations Targets After Cardiac Arrest (BOX)-trial Intensive Care Medicine
Venous return physiology applied to post-cardiac arrest haemodynamic management: a post hoc analysis of the NEUROPROTECT trial Intensive Care Medicine Experimental
VV-ECMO in critical COVID-19 obese patients: a cohort study Journal of Anesthesia, Analgesia and Critical Care
Metadata
Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash