Critical Care Evidence Updates – December 2021
NICE
COVID-19 rapid guideline: managing COVID-19 NG191
Other Guidance/Reports
A guide to enteral nutrition in intensive care units: 10 expert tips for the daily practice Critical Care
Ask. Listen. Act. (2nd edition) (PDF) RCN
Assessment of the further emergence of the SARS-CoV-2 Omicron VOC in the context of the ongoing Delta VOC transmission in the EU/EEA, 18th update (PDF) European Centre for Disease Prevention and Control
COVID-19: Preventing nosocomial infection in older people British Geriatrics Society
Deprivation of liberty safeguards BMA
Physiotherapy management for COVID-19 in the acute hospital setting and beyond: an update to clinical practice recommendations Journal of Physiotherapy
Cochrane
Autogenic drainage for airway clearance in cystic fibrosis
Transfusion thresholds for guiding red blood cell transfusion
Systematic Reviews from Other Sources
Bag-Mask Ventilation Versus Apneic Oxygenation During Tracheal Intubation in Critically Ill Adults: A Secondary Analysis of 2 Randomized Trials Journal of Intensive Care Medicine
Hydrocortisone, ascorbic acid, and thiamine (HAT) for sepsis and septic shock: a meta-analysis with sequential trial analysis Journal of Intensive Care
Inappropriate treatment at the end of life: a systematic review of qualitative evidence (PDF) Evidence for Policy and Practice Information and Co-ordinating Centre
Quality appraisal of guidelines on physical restraints in intensive care units: A systematic review Intensive and Critical Care Nursing
Utilization and outcomes of extracorporeal CO2 removal (ECCO2R): Systematic review and meta-analysis of arterio-venous and veno-venous ECCO2R approaches Artificial Organs
Primary Research
A pilot study of trained ICU doulas providing early psychological support to critically ill patients Critical Care
A qualitative study of nurses’ perception on patients’ thirst in intensive care units Intensive and Critical Care Nursing
Albumin and fibrinogen kinetics in sepsis: a prospective observational study Critical Care
An Evidence-Based Protocol for Manual Prone Positioning of Patients With ARDS Critical Care Nurse
Analysis of Intent and Reason for Oncologic Therapy Administration in Cancer Patients Admitted to the Intensive Care Unit Journal of Intensive Care Medicine
Assessment of Safety of Remdesivir in Covid −19 Patients with Estimated Glomerular Filtration Rate (eGFR) < 30 ml/min per 1.73 m^2 Journal of Intensive Care Medicine
Association between mortality and age among mechanically ventilated COVID-19 patients: a Japanese nationwide COVID-19 database study Annals of Intensive Care
Association of Surge Conditions with Mortality Among Critically Ill Patients with COVID-19 Journal of Intensive Care Medicine
Automated left atrial strain analysis for predicting atrial fibrillation in severe COVID-19 pneumonia: a prospective study Annals of Intensive Care
Awake prone position reduces work of breathing in patients with COVID-19 ARDS supported by CPAP Annals of Intensive Care
Bag valve resuscitator versus Mapleson C circuit during manual ventilation: A bench top study Intensive and Critical Care Nursing
Bleeding and thrombotic events in adults supported with venovenous extracorporeal membrane oxygenation: an ELSO registry analysis Intensive Care Medicine
Characteristics and prognosis of bloodstream infection in patients with COVID-19 admitted in the ICU: an ancillary study of the COVID-ICU study Annals of Intensive Care
Development of a new score for early mortality prediction in trauma ICU patients: RETRASCORE Critical Care
Diagnosing capillary leak in critically ill patients: development of an innovative scoring instrument for non-invasive detection Annals of Intensive Care
Diagnostic Sensitivity of Plasma Endothelin-1 for Cerebral Vasospasm After Subarachnoid Hemorrhage, a Multicentre Double-Blind Study Journal of Intensive Care Medicine
Do alterations in pulmonary vascular tone result in changes in central blood volumes? An experimental study Intensive Care Medicine Experimental
Early Use of Sarilumab in Patients Hospitalised with COVID-19 Pneumonia and Features of Systemic Inflammation. Antimicrobial Agents and Chemotherapy
Effect of a backboard on chest compression quality during in-hospital adult cardiopulmonary resuscitation: A randomised, single-blind, controlled trial using a manikin model Intensive and Critical Care Nursing
Effect of a Multiorgan Focused Clinical Ultrasonography on Length of Stay in Patients Admitted With a Cardiopulmonary Diagnosis A Randomized Clinical Trial JAMA Network Open
Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients – A Randomized Clinical Trial JAMA Internal Medicine
ESCAPE: An Open-Label Trial of Personalized Immunotherapy in Critically ill COVID-19 Patients Journal of Innate Immunity
Etomidate versus ketamine for emergency endotracheal intubation: a randomized clinical trial Intensive Care Medicine
Favorable Outcomes After Implementing a Nurse-Driven Sedation Protocol Critical Care Nurse
Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation After Resuscitation‑2 (RADAR‑2) randomised clinical trial Intensive Care medicine
Flow Index accurately identifies breaths with low or high inspiratory effort during pressure support ventilation Critical Care
Gas conditioning during helmet noninvasive ventilation: effect on comfort, gas exchange, inspiratory effort, transpulmonary pressure and patient–ventilator interaction Annals of Intensive Care
High- Versus Low-Dose Dexamethasone for the Treatment of COVID-19-Related Acute Respiratory Distress Syndrome: A Multicenter, Randomized Open-Label Clinical Trial Journal of Intensive Care Medicine
HSV-1 reactivation is associated with an increased risk of mortality and pneumonia in critically ill COVID-19 patients Critical Care
Implementation of nonpharmacologic physical restraint minimization interventions in the adult intensive care unit: A scoping review Intensive and Critical Care Nursing
Incidence, characteristics and risk factors of medical device-related pressure injuries: An observational cohort study Intensive and Critical Care Nursing
Intensive care unit versus high-dependency care unit for patients with acute heart failure: a nationwide propensity score-matched cohort study Journal of Intensive Care
Intravenous albumin for the prevention of hemodynamic instability during sustained low-efficiency dialysis: a randomized controlled feasibility trial (The SAFER-SLED Study) Annals of Intensive Care
Intravenous iron to treat anaemia following critical care: a multicentre feasibility randomised trial British Journal of Anaesthesia
Lenzilumab in hospitalised patients with COVID-19 pneumonia (LIVE-AIR): a phase 3, randomised, placebo-controlled trial The Lancet Respiratory Medicine
Lung histopathologic clusters in severe COVID-19: a link between clinical picture and tissue damage Critical Care
Mesenchymal stem/stromal cell-based therapies for severe viral pneumonia: therapeutic potential and challenges Intensive Care Medicine Experimental
Molecular mechanisms of postintensive care syndrome Intensive Care Medicine Experimental
Namilumab or infliximab compared with standard of care in hospitalised patients with COVID-19 (CATALYST): a randomised, multicentre, multi-arm, multistage, open-label, adaptive, phase 2, proof-of-concept trial The Lancet Respiratory Medicine
Nurse perceptions of a nurse family liaison implemented during the COVID-19 pandemic: A qualitative thematic analysis Intensive and Critical Care Nursing
Nurse-performed ultrasound assessment of gastric residual volume and enteral nasogastric tube placement in the general intensive care unit Intensive and Critical Care Nursing
Nursing points of interest when nebulizing antibiotics in ventilated patients Intensive and Critical Care Nursing
Patient discharge from intensive care: an updated scoping review to identify tools and practices to inform high-quality care Critical Care
Positive end-expiratory pressure in COVID-19 acute respiratory distress syndrome: the heterogeneous effects Critical Care
Practical strategies for airway clearance in patients with severe COVID-19 Intensive and Critical Care Nursing
Predicting 90-day survival of patients with COVID-19: Survival of Severely Ill COVID (SOSIC) scores Annals of Intensive Care
Predictors for extubation failure in COVID-19 patients using a machine learning approach Critical Care
Propofol as a Drug of Diversion: Changing Disposal Practices to Reduce Risk Critical Care Nurse
Proportional assist ventilation relieves clinically significant dyspnea in critically ill ventilated patients Annals of Intensive Care
Prospective international validation of the predisposition, infection, response and organ dysfunction (PIRO) clinical staging system among intensive care and general ward patients Annals of Intensive Care
Real-world corticosteroid use in severe pneumonia: a propensity-score-matched study Critical Care
Recent Advances in Bedside Device-Based Early Detection of Sepsis Journal of Intensive Care Medicine
Single-dose of adrecizumab versus placebo in acute cardiogenic shock (ACCOST-HH): an investigator-initiated, randomised, double-blinded, placebo-controlled, multicentre trial The Lancet Respiratory Medicine
Stimulating severe COVID-19: the potential role of GM-CSF antagonism The Lancet Respiratory Medicine
Surface EMG-based quantification of inspiratory effort: a quantitative comparison with Pes Critical Care
The effect of the volemic and cardiac status on brain oxygenation in patients with subarachnoid hemorrhage: a bi-center cohort study Annals of Intensive Care
The patient and their family’s perspectives on agitation and its management in adult critical care: A qualitative study Intensive and Critical Care Nursing
Three bedside techniques to quantify dynamic pulmonary hyperinflation in mechanically ventilated patients with chronic obstructive pulmonary disease Annals of Intensive Care
Metadata
Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date: 4th January 2022
Picture by: Ehimetalor Akhere Unuabona on Unsplash