Critical Care Evidence Updates – December 2022
Randomised Controlled Trials
Adjunctive granisetron therapy in patients with sepsis or septic shock (GRANTISS): A single-center, single-blinded, randomized, controlled clinical trial – Frontiers in Pharmacology
Association Between Length of Storage of Transfused Packed RBC Units and Outcome of Surgical Critically Ill Adults: A Subgroup Analysis of the Age of Blood Evaluation Randomized Trial – Critical Care Medicine
Chlorthalidone vs. Hydrochlorothiazide for Hypertension–Cardiovascular Events – NEJM
Colistin Monotherapy versus Combination Therapy for Carbapenem-Resistant Organisms – NEJM Evidence
Continuous peripheral nerve blocks for analgesia of ventilated critically ill patients with multiple trauma: a prospective randomized study – Anaesthesia Critical Care & Pain Medicine
Effect of clinical peer review on mortality in patients ventilated for more than 24 hours: a cluster randomised controlled trial – BMJ Quality and Safety
Evaluation of a closed loop-blood sampling system in intensive care: A pilot randomised controlled trial. The ENCLOSE trial – Intensive and Critical Care Nursing
Haloperidol for the Treatment of Delirium in ICU Patients – NEJM
Hemoperfusion for Clinically Suspected Organophosphate and Carbamate Poisoning in Critically Ill Patients: A Randomized Trial – Blood Purification
Isoflurane vs. propofol for sedation in invasively ventilated patients with acute hypoxemic respiratory failure: an a priori hypothesis substudy of a randomized controlled trial – Annals of Intensive Care
Mannitol for prevention of acute kidney injury after liver transplantation: a randomized controlled trial – BMC Anesthesiology
Melatonin for prevention of acute kidney injury in patients treated with intravenous polymyxin B: a double-blind, placebo-controlled randomised clinical trial – Clinical Microbiology and Infection
Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia – NEJM
The effect of abdominal massage on enteral nutrition tolerance in patients on mechanical ventilation: A Randomized Controlled Study – Intensive and Critical Care Nursing
The effects of a sensory stimulation intervention on psychosocial and clinical outcomes of critically ill patients and their families: A randomised controlled trial – Intensive and Critical Care Nursing
Thromboelastometry-guided treatment algorithm in postpartum haemorrhage: a randomised, controlled pilot trial – British Journal of Anaesthesia
Ultrasound-Guided Infraclavicular Axillary Vein Versus Internal Jugular Vein Cannulation in Critically Ill Mechanically Ventilated Patients: A Randomized Trial – Critical Care Medicine
Other Guidance/Reports
Canadian Stroke Best Practice Recommendations: Acute Stroke Management, 7th Edition Practice Guidelines Update, 2022 – Canadian Journal of Neurological Sciences
Expert consensus on the monitoring and treatment of sepsis-induced immunosuppression – Military Medical Research
Guidelines for Reporting Outcomes in Trial Protocols – The SPIRIT-Outcomes 2022 Extension – JAMA
Randomized Trials Fit for the 21st Century: A Joint Opinion From the European Society of Cardiology, American Heart Association, American College of Cardiology, and the World Heart Federation – Journal of the American College of Cardiology
Primary Research
A multicentric prospective observational study of diagnosis and prognosis features in ICU mesenteric ischemia: the DIAGOMI study – Annals of Intensive Care
A novel method to calculate compliance and airway resistance in ventilated patients – Intensive Care Medicine Experimental
Abdominal atherosclerosis is not a risk factor of nonocclusive mesenteric ischemia among critically ill patients: a propensity matching study – Annals of Intensive Care
Anemia before in-hospital cardiac arrest and survival from cardio-pulmonary resuscitation—a retrospective cohort study – Journal of Anesthesia, Analgesia and Critical Care
Angiotensin II for Vasodilatory Hypotension in Patients Requiring Mechanical Circulatory Support – Journal of Intensive Care Medicine
Assessment of Good Practice Guidelines for Administration of Drugs via Feeding Tubes by a Clinical Pharmacist in the Intensive Care Unit – Critical Care Nurse
Association between age and the host response in critically ill patients with sepsis – Critical Care
Association between cholinesterase activity and critical illness brain dysfunction – Critical Care
“At the end, we are all human” – Striving for equity in the care of patients from culturally diverse backgrounds – Intensive and Critical Care Nursing
Auto-antibodies against type I IFNs in > 10% of critically ill COVID-19 patients: a prospective multicentre study – Annals of Intensive Care
Brain injury markers in blood predict signs of hypoxic ischaemic encephalopathy on head computed tomography after cardiac arrest – Resuscitation
Cerebrovascular complications and outcomes of critically ill adult patients with infective endocarditis – Annals of Intensive Care
Cerebrovascular pressure reactivity and brain tissue oxygen monitoring provide complementary information regarding the lower and upper limits of cerebral blood flow control in traumatic brain injury: a CAnadian High Resolution-TBI (CAHR-TBI) cohort study – Intensive Care Medicine Experimental
Changing epidemiology of acute kidney injury in critically ill patients with COVID-19: a prospective cohort – Annals of Intensive Care
Circular material flow in the intensive care unit—environmental effects and identification of hotspots – Intensive Care Medicine
Comparing rehabilitation outcomes for patients admitted to the intensive care unit with COVID-19 requiring mechanical ventilation during the first two waves of the pandemic: A service evaluation – Intensive and Critical Care Nursing
Coronavirus disease 2019 aftermath: psychological trauma in ICU healthcare workers – Current Opinion in Critical Care
COVID-19-associated AKI – Current Opinion in Critical Care
Critical Care and Postoperative Management of the First Human Long Segment Orthotopic Tracheal Transplantation – Critical Care Explorations
Diaphragm Neurostimulation Mitigates Ventilation-Associated Brain Injury in a Preclinical Acute Respiratory Distress Syndrome Model – Critical Care Explorations
Effect of Admission and Discharge Times on Hospital Mortality in Patients With Sepsis – Critical Care Medicine
Effect of an educational intervention on compliance with care bundle items to prevent ventilator-associated pneumonia – Intensive and Critical Care Nursing
Effects of changes in inspired oxygen fraction on urinary oxygen tension measurements – Intensive Care Medicine Experimental
Examining the needs of survivors of critical illness through the lens of palliative care: A qualitative study of survivor experiences – Intensive and Critical Care Nursing
Frailty is a stronger predictor of death in younger intensive care patients than in older patients: a prospective observational study – Annals of Intensive Care
Gene signature for the prediction of the trajectories of sepsis-induced acute kidney injury – Critical Care
Healthcare trajectory of critically ill patients with necrotizing soft tissue infections: a multicenter retrospective cohort study using the clinical data warehouse of Greater Paris University Hospitals – Annals of Intensive Care
How do nurses manage their work under time pressure? Occurrence of implicit rationing of nursing care in the intensive care unit: A qualitative study – Intensive and Critical Care Nursing
Improving ICU Risk Predictive Models Through Automation Designed for Resiliency Against Documentation Bias – Critical Care Medicine
Intellectually disabled patients’ intensive care admission characteristics, weaning from mechanical ventilation, and sedative drug use: a single-center retrospective case-control study – Journal of Anesthesia, Analgesia and Critical Care
Management of transgender patients in critical care – Journal of the Intensive Care Society
Mechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study – Journal of Intensive Care
Mechanical ventilation variables associated with high pulmonary artery pressures in ARDS patients: a post hoc analysis – Critical Care
Methods for calculating ventilation rates during resuscitation from out-of-hospital cardiac arrest – Resuscitation
Mild hypothermia combined with dexmedetomidine reduced brain, lung, and kidney damage in experimental acute focal ischemic stroke – Intensive Care Medicine Experimental
Outcomes and Adverse Effects of Baricitinib Versus Tocilizumab in the Management of Severe COVID-19
Critical Care Medicine
Perioperative outcomes in intermediate and high-risk patients after major surgery following introduction of a dedicated perioperative medicine team: A single centre cohort study – Anaesthesia and Intensive Care
Perspectives and wishes for patient and family centred care as expressed by adult intensive care survivors and family-members: A qualitative interview study – Intensive and Critical Care Nursing
Physical, social, mental and spiritual functioning of COVID-19 intensive care unit-survivors and their family members one year after intensive care unit-discharge: A prospective cohort study – Intensive and Critical Care Nursing
Prediction of noninvasive ventilation failure using the ROX index in patients with de novo acute respiratory failure – Annals of Intensive Care
Predicting Readmission or Death After Discharge From the ICU: External Validation and Retraining of a Machine Learning Model – Critical Care Medicine
Prognostic significance of delirium subtypes in critically ill medical and surgical patients: a secondary analysis of a prospective multicenter study – Journal of Intensive Care
Real-time 4D transesophageal echocardiography in the evaluation of cardioaortic embolism: the value of completing a comprehensive protocol – Intensive Care Medicine
Score-based prediction model for severe vitamin D deficiency in patients with critical illness: development and validation – Critical Care
The effect of music on delirium, pain, sedation and anxiety in patients receiving mechanical ventilation in the intensive care unit – Intensive and Critical Care Nursing
The Impact of Thoracic Ultrasound on Clinical Management of Critically Ill Patients (UltraMan): An International Prospective Observational Study – Critical Care Medicine
The importance of nutrition to morbidity and mortality in critically ill patients – Intensive and Critical Care Medicine
The prevalence of mental frailty in ICU survivors and informal caregiver strain: A 1-year retrospective study of the Frisian aftercare cohort – Journal of the Intensive Care Society
Timing of tracheostomy and patient outcomes in critically ill patients requiring extracorporeal membrane oxygenation: a single-center retrospective observational study – Journal of Intensive Care
Metadata
Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash
