Critical Care Evidence Updates – October 2022
Randomised Controlled Trials
A Randomized Pilot Study Assessing if SEDLine Monitoring During Induction of Surgical Patients is Associated With Reduced Dosage of Administered Induction Agents Seminars in Cardiothoracic and Vascular Anesthesia
A Randomised trial of anti–GM-CSF Otilimab in severe COVID-19 pneumonia (OSCAR) European Respiratory Journal
Analgesic efficacy of the bilateral erector spinae plane block for colorectal surgery: a randomized controlled trial Journal of Anesthesia, Analgesia and Critical Care
Avdoralimab (Anti-C5aR1 mAb) Versus Placebo in Patients With Severe COVID-19: Results From a Randomized Controlled Trial (FOR COVID Elimination [FORCE]) Critical Care Medicine
Comparison of ultrasound-guided internal jugular vein and supraclavicular subclavian vein catheterization in critically ill patients: a prospective, randomized clinical trial Annals of Intensive Care
Decompressive Craniectomy for the Treatment of Severe Diffuse Traumatic Brain Injury: A Randomized Controlled Trial Asian Journal of Neurosurgery
Early Active Mobilization during Mechanical Ventilation in the ICU NEJM
Haloperidol for the Treatment of Delirium in ICU Patients NEJM
Invasive Diagnostic and Therapeutic Management of Cerebral VasoSpasm after Aneurysmal Subarachnoid Hemorrhage (IMCVS)—A Phase 2 Randomized Controlled Trial Journal of Clinical Medicine
Levetiracetam versus fosphenytoin as a second-line treatment after diazepam for adult convulsive status epilepticus: a multicentre non-inferiority randomised control trial Journal of Neurology, Neurosurgery & Psychiatry
Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation NEJM
Percutaneous Revascularization for Ischemic Left Ventricular Dysfunction NEJM
Randomized Phase 3 Trial of Ruxolitinib for COVID-19–Associated Acute Respiratory Distress Syndrome Critical Care Medicine
Spontaneous-Breathing Trials with Pressure-Support Ventilation or a T-Piece NEJM
The cardioprotective and anti-inflammatory effect of inhaled nitric oxide during Fontan surgery in patients with single ventricle congenital heart defects: a prospective randomized study Journal of Intensive Care
Tocilizumab versus baricitinib in hospitalized patients with severe COVID-19: an open label, randomized controlled trial. Clinical Microbiology and Infection
Trial of Endovascular Treatment of Acute Basilar-Artery Occlusion NEJM
Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion NEJM
Volatile Versus Total Intravenous Anesthesia on Postoperative Delirium in Adult Patients Undergoing Cardiac Valve Surgery: A Randomized Clinical Trial Anaesthesia & Analgesia
Other Guidance/Reports
Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery World Journal of Emergency Surgery
EFSUMB Clinical Practice Guidelines for Point-of-Care Ultrasound: Part One (Common Heart and Pulmonary Applications) LONG VERSION European Journal of Ultrasound
Expert consensus on the diagnosis and treatment of severe and critical coronavirus disease 2019 (COVID-19) Journal of Intensive Medicine
Follow-up strategies for patients with splenic trauma managed non-operatively: the 2022 World Society of Emergency Surgery consensus document World Journal of Emergency Surgery
Lung-protective sedation: moving toward a new paradigm of precision sedation Intensive Care Medicine
Processed Electroencephalogram-Based Monitoring to Guide Sedation in Critically Ill Adult Patients: Recommendations from an International Expert Panel-Based Consensus Neurocritical Care
Ten areas for ICU clinicians to be aware of to help retain nurses in the ICU Critical Care
Cochrane
Non‐invasive positive pressure ventilation for central sleep apnoea in adults
Primary Research
A burden of fluid, sodium, and chloride due to intravenous fluid therapy in patients with respiratory support: a post-hoc analysis of a multicenter cohort study Annals of Intensive Care
A multidisciplinary safety briefing for acutely ill and deteriorating patients: A quality improvement project Intensive and Critical Care Nursing
Accuracy of clinicians’ ability to predict the need for renal replacement therapy: a prospective multicenter study Annals of Intensive Care
Agitation is a Common Barrier to Recovery of ICU Patients Journal of Intensive Care Medicine
Assessment of Admission COVID-19 Associated Hyperinflammation Syndrome Score in Critically-Ill COVID-19 Patients Journal of Intensive Care Medicine
Association Between Daily Average of Mobility Achieved During Physical Therapy Sessions and Hospital-Acquired or Ventilator-Associated Pneumonia among Critically Ill Patients Journal of Intensive Care Medicine
Association between in-ICU red blood cells transfusion and 1-year mortality in ICU survivors Critical Care
Association of early dexamethasone therapy with mortality in critically Ill COVID-19 patients: a French multicenter study Annals of Intensive Care
Awake prone positioning for patients with COVID-19-induced acute hypoxemic respiratory failure Journal of Intensive Medicine
Characteristics and outcomes of surgical patients admitted to an overnight intensive recovery unit: A retrospective observational study Anaesthesia and Intensive Care
Chest dual-energy CT to assess the effects of steroids on lung function in severe COVID-19 patients Critical Care
Circular RNAs to predict clinical outcome after cardiac arrest Intensive Care Medicine Experimental
Circulating N-formylmethionine and metabolic shift in critical illness: a multicohort metabolomics study Critical Care
Comparison of Different Ultrasound Methods to Assess Changes in Muscle Mass in Critically ill Patients Journal of Intensive Care Medicine
Criteria deemed important by ICU patients when designating a reference person Journal of Intensive Medicine
Delivery decision in pregnant women rescued by ECMO for severe ARDS: a retrospective multicenter cohort study Critical Care
Development and validation of a user-friendly risk nomogram for the prediction of catheter-associated urinary tract infection in neuro-intensive care patients Intensive and Critical Care Nursing
Epidemiology of ICU-Onset Bloodstream Infection: Prevalence, Pathogens, and Risk Factors Among 150,948 ICU Patients at 85 U.S. Hospitals Critical Care Medicine
Etoposide treatment in secondary hemophagocytic syndrome: impact on healthcare-associated infections and survival Annals of Intensive Care
Evolution of respiratory system compliance and potential for lung recruitment in COVID-19–induced acute respiratory distress syndrome Journal of Intensive Medicine
Functional Recovery Groups in Critically Ill COVID-19 Patients and Their Associated Factors: From ICU to Hospital Discharge Critical Care Medicine
High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI Intensive Care Medicine
Impact of Dual Intensive Care Unit and Rapid Response Team Nursing Roles on Service Delivery in the Intensive Care Unit Critical Care Nurse
Improving Communication and Response to Clinical Deterioration to Increase Patient Safety in the Intensive Care Unit Critical Care Nurse
Improving Initial Sepsis Management Through a Nurse-Driven Rapid Response Team Protocol Critical Care Nurse
In-hospital Outcomes of Patients with Septic Shock and Underlying Chronic Atrial Fibrillation: A Propensity Matched Analysis from A National Dataset Journal of Intensive Care Medicine
Low-Flow Duration and Outcomes of Extracorporeal Cardiopulmonary Resuscitation in Adults With In-Hospital Cardiac Arrest: A Nationwide Inpatient Database Study Critical Care Medicine
Microcirculatory alterations in critically ill COVID-19 patients analyzed using artificial intelligence Critical Care
Outcomes of mild-to-moderate postresuscitation shock after non-shockable cardiac arrest and association with temperature management: a post hoc analysis of HYPERION trial data Annals of Intensive Care
Patient and Caregiver-Derived Health Service Improvements for Better Critical Care Recovery Critical Care Medicine
Patient mobilisation in the intensive care unit and evaluation of a multifaceted intervention including Facebook groups: A quasi-experimental study Intensive and Critical Care Nursing
Predicting responders to prone positioning in mechanically ventilated patients with COVID-19 using machine learning Annals of Intensive Care
Preparing for the Worst-Case Scenario in a Pandemic: Intensivists Simulate Prioritization and Triage of Scarce ICU Resources Critical Care Medicine
Preventing Medical Device–Related Pressure Injuries Due to Noninvasive Ventilation Masks and Nasal Cannulas Critical Care Nurse
Prone positioning in ARDS patients supported with VV ECMO, what we should explore? Journal of Intensive Care
Pupillary dilation reflex and behavioural pain scale: Study of diagnostic test Intensive and Critical Care Nursing
Right ventricular strain measurements in critically ill patients: an observational SICS sub-study Annals of Intensive Care
Serial Measurements of Protein Biomarkers in Sepsis-Induced Acute Respiratory Distress Syndrome Critical Care Explorations
Short- versus long-course antibiotic therapy for sepsis: a post hoc analysis of the nationwide cohort study Journal of Intensive Care
Strategies for a safe interhospital transfer with an intubated patient or where readiness for intubation is needed: A critical incidents study Intensive and Critical Care Nursing
T cell dysregulation in inflammatory diseases in ICU Intensive Care Medicine Experimental
The association of intensive care capacity transfers with survival in COVID-19 patients from a Scottish district general hospital: A retrospective cohort study Journal of the Intensive Care Society
The effect of post-reperfusion levosimendan in an experimental intestinal ischemia–reperfusion model Journal of Anesthesia, Analgesia and Critical Care
The relationship between secondary traumatic stress and burnout in critical care nurses: The mediating effect of resilience Intensive and Critical Care Nursing
Trends in mortality in septic patients according to the different organ failure during 15 years Critical Care
What airway management information do anaesthetic charts prompt for? An audit of charts from 132 hospitals across Australia and New Zealand Anaesthesia and Intensive Care
Metadata
Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash