Emergency Evidence Updates – September 2025

Randomised Controlled Trials
Effect of a portable therapeutic baby nest designed for neonates on physiological parameters, comfort and pain levels during venous blood sampling: a randomised controlled trial Emergency Medicine Journal
Effect of Distracting Methods on Procedure-Related Fear, Anxiety, and Pain During Intramuscular Injection: A Randomized Controlled Trial Journal of Emergency Nursing
Factors in the Initial Resuscitation of Patients With Severe Trauma – The FiiRST-2 Randomized Clinical Trial JAMA Network Open
Health Services and Economic Impacts of the Limit of Detection in Emergency Department (LEGEND) Rule-Out Strategy in Australian Emergency Departments: A Stepped-Wedge Cluster Randomised Trial Emergency Medicine Australasia
Non-pharmacological de-escalation techniques used to manage acute severe behavioural disturbance in children and adolescents presenting to emergency departments: secondary analysis of a randomised controlled trial Archives of Disease in Childhood
Optimal Dose of Intranasal Midazolam for Procedural Sedation in Children – A Randomized Clinical Trial JAMA Pediatrics
Peripheral Perfusion vs Standard Management in Sepsis/Septic Shock: A Prospective Randomized ED Study The American Journal of Emergency Medicine
The Effectiveness of Intranasal Ketamine on Intramuscular Ketamine Injection Pain Among Children in the Emergency Department, a Randomized, Controlled Trial Pediatric Emergency Care
NICE
Pneumonia: diagnosis and management NG250
Pneumonia: diagnosis and management QS110
Other Guidance/Reports
PIER
Primary Research
Prehospital
Admission Hypothermia in Trauma Patients Undergoing Prehospital Tracheal Intubation: 15-Year Review of a Level-1 Trauma Center Prehospital Emergency Care
‘Every day was a learning curve’: implementing COVID-19 triage protocols in UK ambulance services—a qualitative study of staff experiences Emergency Medicine Journal
Implementing prehospital invasive arterial blood pressure monitoring in critically ill patients—a prospective observational first year analysis Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Pre-hospital THRIVE score predicts the thrombolysis in cerebral infarction outcome post endovascular thrombectomy: an emergency medical service study BMC Emergency Medicine
General
A Pilot Study Using Casino Shifts to Improve Sleep for Emergency Medicine Fellows Working Night Shifts Pediatric Emergency Care
Building a psychiatric boarding toolkit: an emergency nursing perspective on a collaborative approach to care The Journal of Emergency Medicine
Detecting acute ischemic lesions using mobile, low-field MRI in TIA and minor stroke in the emergency room International Journal of Stroke
Effectiveness of a Smartwatch-Based Feedback System in Improving Cardiopulmonary Resuscitation Quality: A Simulation Study Resuscitation Plus
Emergency physicians’ perspectives on integrating physiotherapists into emergency departments: a national survey from France Emergency Medicine Journal
Foley Tubing as a Luer Adapter for Thoracic Lavage in Severe Hypothermia The Journal of Emergency Medicine
Machine learning model to predict mortality in patients with skin and soft tissue infection in emergency department Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Perceived Relationships Between Emergency Department Staffing Patterns and Missed Care, Missed Decompensation, and Delays in Care Journal of Emergency Nursing
Performance of ChatGPT, Gemini and DeepSeek for non-critical triage support using real-world conversations in emergency department BMC Emergency Medicine
The Impact of Interim Care Plans for Direct Inpatient Admissions on Emergency Department Length of Stay: A Retrospective Single-Site Matched-Cohort Study Emergency Medicine Australasia
Paediatrics
Association of Suicide Risk Factors and Subsequent Pediatric Emergency Department Mental Health Visits Pediatric Emergency Care
Characteristics of Young Children Presenting to the Emergency Department for Psychiatric Evaluation The Journal of Emergency Medicine
Child death in the emergency department: experience from a 10-year retrospective review Archives of Disease in Childhood
Clinical Pathway Revision Increases Amoxicillin Monotherapy and 5-Day Durations of Therapy for Pediatric Community-Acquired Pneumonia in the Emergency Department and Urgent Care: A Quality Improvement Initiative Annals of Emergency Medicine
Experiences of Pediatricians Caring for Children and Adolescents With Mental Health Needs in the Emergency Department, 2022 Pediatric Emergency Care
Gonorrhea and Chlamydia Screening for Adolescents and Young Adults in Emergency Departments JAMA Pediatrics
Herpes simplex virus disease in infants younger than 90 days: a British Paediatric Surveillance Unit study Archives of Disease in Childhood
Improving Antibiotic Administration Time in At-Risk Pediatric Populations: A Quality Improvement Project Journal of Emergency Nursing
Measured Serum Osmolality as a Severity Marker of Pediatric Hyperglycemic Crises Pediatric Emergency Care
Not so FAST! Review of Adolescent Point-of-Care Ultrasound Reveals Splenic Mass Requiring Splenectomy Pediatric Emergency Care
Opioid Timeliness in the Emergency Department and Hospitalizations for Acute Sickle Cell Pain JAMA Pediatrics
Optimizing CPR performance: the role of body composition and ergonomic positioning BMC Emergency Medicine
Point-of-Care Ultrasound Evaluation of Biliary Atresia in the Pediatric Emergency Department Pediatric Emergency Care
Predicting Pediatric Cardiac Arrest Outcomes Using Early Quantitative EEG Resuscitation
Resource Utilization for Brief Resolved Unexplained Events in a Pediatric and General Emergency Department Pediatric Emergency Care
Sentinel Injuries in Emergency Departments and Subsequent Serious Injury in Children Annals of Emergency Medicine
Tissue Adhesive as an Alternative to Sutures in Pediatric Eye Emergency – A Clinical Prospective Comparative Cohort Study Pediatric Emergency Care
Validating the PECARN rule to identify febrile infants at low risk of serious bacterial infections: an international validation study Archives of Disease in Childhood
Adults
Accuracy of Published Screening Tools for Large Vessel Occlusion in Patients With Suspected Acute Ischemic Stroke: A Prospective Cohort Study Annals of Emergency Medicine
Antibiotic Therapy for Pyelonephritis in the Emergency Department Emergency Medicine Australasia
Association of Troponin Elevation with Cardiovascular Event in Stable Supraventricular Tachycardia in the Emergency Department The Journal of Emergency Medicine
Computed Tomography Head Ordering Practices in Residential Aged Care Facility Residents Presenting to Emergency Department After an Unwitnessed Fall Emergency Medicine Australasia
Horsing Around: A Retrospective Study of Equestrian Related Eye Injuries in the Emergency Department The Journal of Emergency Medicine
Is our understanding of Hyperosmolar Hyperglycemic State accurate? The Journal of Emergency Medicine
Patients and hospital staff perceive diverting patients from the emergency department to physiotherapy outpatients as safe and effective: a qualitative descriptive study Physiotherapy Theory and Practice
Recall incidence After Procedural Sedation with Propofol in Emergency Departments The Journal of Emergency Medicine
Serious Cardiac Outcomes and Physician Estimation of Risk in Emergency Department Patients With Presyncope Versus Syncope Annals of Emergency Medicine
The stiff leg sign in acute thigh & gluteal compartment syndrome: A case report Trauma
Metadata
Summary author: Rebecca Howes
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash
