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Does chlorhexidine-impregnated dressing compared to conventional site care prevent catheter-related blood stream infections and catheter colonisation?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
These are summaries of trials published in 2014.
Does chlorhexidine-impregnated dressing compared to conventional site care prevent catheter-related blood stream infections and catheter colonisation?
Continue reading »In patients with severe sepsis or septic shock, is the timing of first administration of antibiotics associated with the in-hospital mortality rate?
Continue reading »In patients with PE, does the addition of thrombolysis to anticoagulation, compared with anticoagulation alone, affect mortality and bleeding complications?
Continue reading »In patients with submassive PE, does the use of tenecteplase + heparin, compared to heparin alone, improve patient orientated outcomes?
Continue reading »In patients with septic shock does a high target mean arterial pressure (MAP), compared to a low target MAP, improve mortality?
Continue reading »In patients with suspected acute coronary syndrome does a rapid diagnostic pathway allow early discharge from hospital without more adverse effects when compared with a conventional diagnostic assessment and discharge plan?
Continue reading »In high-risk patients undergoing gastrointestinal surgery, does a cardiac output-guided haemodynamic therapy algorithm compared to clinician-guided standard therapy reduce death and major morbidity within 30 days?
Continue reading »In adults with severe sepsis or septic shock, does 20% albumin solution with crystalloid fluid compared to crystalloid fluid alone reduce death with 28 days?
Continue reading »In adult patients with sepsis, does protocol-based care compared to usual care reduce death within 60 days?
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