SPICE III
In ventilated, critically ill patients, does the use of dexmedetomidine as the primary sedative agent compared with usual sedative agents effect 90 day mortality?
Continue reading »Year: 2019
PreVent
In adult ICU patients undergoing tracheal intubation, does bag mask ventilation (BMV) between induction and laryngoscopy reduce the risk of hypoxaemia?
Continue reading »MAPAS
Early Manipulation of Arterial Blood Pressure in Acute Ischemic Stroke(MAPAS):Results of a Randomized Controlled Trial Luiz Antonio Nasi. Neurocritical Care 2019; doi: https://doi.org/10.1007/s12028-018-0642-5 Clinical Question In adult patients presenting within 12 hours of an acute ischaemic stroke (AIS), which of three targeted and pre-specified systolic blood pressure (SBP) ranges results in an improved functional outcome at 90 days? Background Significant […]
Continue reading »SHoC-ED 3
In patients presenting to the Emergency Department (ED) in cardiac arrest, does a standardised point-of-care ultrasound protocol, compared with usual care, affect the length of resuscitation, frequency of interventions, and clinical outcomes?
Continue reading »EVALD
In patients that survive with a good neurological outcome following out-of-hospital cardiac arrest, does 48 hours vs. 24 hours of therapeutic hypothermia, improve memory, attention & executive function at 6 months?
Continue reading »COACT
In adult patients who have sustained an out of hospital arrhythmia-associated cardiac arrest without an ST-elevation myocardial infarction, is immediate angiography superior to delayed angiography in improving 90-day survival?
Continue reading »SUPERNOVA
Can extracorporeal carbon dioxide removal (ECCO2R) safely facilitate ultra-low tidal volume ventilation in patients with moderate acute respiratory distress syndrome (ARDS)?
Continue reading »ANDROMEDA-SHOCK
In adult patients with early septic shock, does peripheral perfusion-targeted resuscitation, compared to lactate level-targeted resuscitation, improve all cause mortality at 28 days?
Continue reading »PREVENT
In adult critically ill patients receiving pharmacological thromboprophylaxis, does the use of adjunctive intermittent pneumatic compression devices result in a lower incidence of proximal deep vein thrombosis (DVT)?
Continue reading »Pivetta
In patients who presented to the Emergency Department (ED) with acute dyspnoea, does the addition of lung ultrasound examination compared to standard approach, improve the diagnostic accuracy for acute decompensated heart failure (ADHF)?
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