TRACT Transfusion Volume

Transfusion Volume for Children with Severe Anaemia in Africa K.Maitland. New England Journal of Medicine August 1st 2019; 381:5; 420-431. doi: 10.1056/NEJMoa1900100 Clinical Question In African children presenting to hospital with severe anaemia, is a blood transfusion volume of 30 ml/kg superior to 20 ml/kg in reducing 28 day mortality? Background Severe anaemia is a major cause of death and […]

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MAPAS

Early Manipulation of Arterial Blood Pressure in Acute Ischemic Stroke(MAPAS):Results of a Randomized Controlled Trial Luiz Antonio Nasi. Neurocritical Care 2019; doi: https://doi.org/10.1007/s12028-018-0642-5 Clinical Question In adult patients presenting within 12 hours of an acute ischaemic stroke (AIS), which of three targeted and pre-specified systolic blood pressure (SBP) ranges results in an improved functional outcome at 90 days? Background Significant […]

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