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In critically ill adults, does the use of an intubating stylet compared to tracheal tube alone, increase first-attempt successful intubation?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
In critically ill adults, does the use of an intubating stylet compared to tracheal tube alone, increase first-attempt successful intubation?
Continue reading »In patients with septic shock, does the use of intravenous vitamin C and thiamine compared to standard therapy improve recovery from organ failure?
Continue reading »Prevention of Early Ventilator-Associated Pneumonia after Cardiac Arrest Francois et al. N Engl J Med 2019;381:1831-42. DOI: 10.1056/NEJMoa1812379 Clinical Question In post out-of-hospital cardiac arrest patients treated with targeted temperature management, does the use of empirical antibiotics prevent early ventilator-associated pneumonia? Background Rates of survival to hospital discharge and good neurological outcomes post out-of-hospital cardiac arrest (OOHCA) remain poor Despite […]
Continue reading »In severely injured trauma patients, where anticoagulation is contraindicated, does the use of prophylactic inferior vena cava filters reduce the incidence of pulmonary embolism (PE)?
Continue reading »In patients presenting to the Emergency Department (ED) in cardiac arrest, does a standardised point-of-care ultrasound protocol, compared with usual care, affect the length of resuscitation, frequency of interventions, and clinical outcomes?
Continue reading »In patients who presented to the Emergency Department (ED) with acute dyspnoea, does the addition of lung ultrasound examination compared to standard approach, improve the diagnostic accuracy for acute decompensated heart failure (ADHF)?
Continue reading »In ICU patients at risk of gastrointestinal (GI) bleeding does the use of prophylactic proton-pump inhibitor (PPI) compared to placebo reduce mortality at 90 days?
Continue reading »In patients with acute myocardial infarction complicated by cardiogenic shock and evidence of multi-vessel disease on early diagnostic angiography, does immediate multi-vessel percutaneous coronary intervention (PCI) compared to culprit lesion only PCI (with staged revascularisation) improve outcome?
Continue reading »In critically ill patients with septic shock, does the use of terlipressin compared to norepinephrine reduced 28-day mortality?
Continue reading »In critically ill patients with septic shock, does the combination of hydrocortisone plus fludrocortisone therapy reduce 90 day mortality?
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