Critical Care Evidence Updates – January 2023
Randomised Controlled Trials
Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture NEJM
Association between driving pressure and postoperative pulmonary complications in patients undergoing lung resection surgery: A randomised clinical trial Anaesthesia Critical Care & Pain Medicine
Continued enteral nutrition until extubation compared with fasting before extubation in patients in the intensive care unit: an open-label, cluster-randomised, parallel-group, non-inferiority trial The Lancet Respiratory Medicine
Cytokine hemoadsorption with CytoSorb® in post-cardiac arrest syndrome, a pilot randomized controlled trial Critical Care
Development and validation of a multivariable model predicting the required catheter dwell time among mechanically ventilated critically ill patients in three randomized trials Annals of Intensive Care
Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension (RCT) NEJM
Effect of non-invasive ventilation after extubation in critically ill patients with obesity in France: a multicentre, unblinded, pragmatic randomised clinical trial The Lancet Respiratory Medicine
Effectiveness of an intensive care telehealth programme to improve process quality (ERIC): a multicentre stepped wedge cluster randomised controlled trial Intensive Care Medicine
Electric impedance tomography-guided PEEP titration reduces mechanical power in ARDS: a randomized crossover pilot trial Critical Care
Hypertonic saline infusion does not improve the chance of primary fascial closure after damage control laparotomy: a randomized controlled trial World Journal of Emergency Surgery
Postoperative prophylactic intermittent noninvasive ventilation versus usual postoperative care for patients at high risk of pulmonary complications: a multicentre randomised trial British Journal of Anaesthesia
Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients – A randomized controlled trial Journal of Critical Care
The Effect of L-Citrulline Supplementation on Outcomes of Critically Ill Patients under Mechanical Ventilation; a Double-Blind Randomized Controlled Trial Archives of Academic Emergency Medicine
The prevalence of sepsis-induced coagulopathy in patients with sepsis – a secondary analysis of two German multicenter randomized controlled trials Annals of Intensive Care
Valproic acid as adjuvant treatment for convulsive status epilepticus: a randomised clinical trial Critical Care
NICE
Delirium: prevention, diagnosis and management in hospital and long-term care CG103
Other Guidance/Reports
2022 SPILF – Clinical Practice Guidelines for the Diagnosis and Treatment of Disco-Vertebral Infection in Adults – Infectious Diseases Now
Anaesthetic and peri-operative management for thrombectomy procedures in stroke patients – Anaesthesia Critical Care & Pain Medicine
Implementing human factors in anaesthesia: guidance for clinicians, departments and hospitals – Guidelines from the Difficult Airway Society and the Association of Anaesthetists – Association of Anaesthetists
Prevention of upper gastrointestinal bleeding in critical illness – Intensive Care Medicine
Ten recommendations for child-friendly visiting policies in critical care – Intensive Care Medicine
The Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19: Antigen Testing – Clinical Infectious Diseases
Cochrane
Hyperimmune immunoglobulin for people with COVID‐19
Medication review in hospitalised patients to reduce morbidity and mortality
Remdesivir for the treatment of COVID‐19
Risk of thromboembolism in patients with COVID‐19 who are using hormonal contraception
Primary Research
A deep learning model for the classification of atrial fibrillation in critically ill patients Intensive Care Medicine Experimental
Age-adjusted Charlson Comorbidity Index as effective predictor for in-hospital mortality of patients with cardiac arrest: a retrospective study BMC Emergency Medicine
Association between acute disease severity and one-year quality of life among post-hospitalisation COVID-19 patients: Coalition VII prospective cohort study Intensive Care Medicine
Cardiovascular Subphenotypes in Acute Respiratory Distress Syndrome Critical Care Medicine
Clinical effectiveness of tigecycline in combination therapy against nosocomial pneumonia caused by CR-GNB in intensive care units: a retrospective multi-centre observational study Journal of Intensive Care
Early management of isolated severe traumatic brain injury patients in a hospital without neurosurgical capabilities: a consensus and clinical recommendations of the World Society of Emergency Surgery (WSES) World Journal of Emergency Medicine
Electrical Impedance Tomography As a Bedside Diagnostic Tool for Pulmonary Embolism Critical Care Explorations
Evaluation of Dexmedetomidine as an Adjunct to Phenobarbital for Alcohol Withdrawal in Critically Ill Patients Journal of Intensive Care Medicine
Evaluation of Early Tocilizumab Effect on Multiorgan Dysfunction in Critically Ill Patients With COVID-19: A Propensity Score-Matched Study Journal of Intensive Care Medicine
Identifying Predictors of Extubation on the day of Passing an SBT in Critically ill Adults Journal of Intensive Care Medicine
Impact of Alcohol Misuse on Requirements for Critical Care Services and Development of Hospital Delirium in Patients With COVID-19 pneumonia Critical Care Explorations
Impact of Time to Intervention on Catheter-Directed Therapy for Pulmonary Embolism Critical Care Explorations
Implementation and Impact of Critical Care Pharmacist Addition to a Telecritical Care Network Critical Care Explorations
Operation clean up: A model for eco-leadership and sustainability implementation Anaesthesia and Intensive Care
Perioperative changes in fluid distribution and haemodynamics in acute high-risk abdominal surgery Critical Care
Post-cardiac surgery fungal mediastinitis: clinical features, pathogens and outcome Critical Care
Relationship Among Clinically Obtained Biomarkers of Inflammation, Hypercoagulability, and Macrophage Activation, and Delirium in Critically Ill Patients With COVID-19 Critical Care Explorations
Role of nebulized colistin as a substitutive strategy against nosocomial pneumonia caused by CR-GNB in intensive care units: a retrospective cohort study Annals of Intensive Care
Severity scores for status epilepticus in the ICU: systemic illness also matters Critical Care
Simulation training results in performance retention for the management of airway fires: A prospective observational study Anaesthesia and Intensive Care
The Early Impact of COVID-19 on Intensive Care Nurses’ Personal and Professional Well-Being: A Qualitative Study Intensive and Critical Care Nursing
Urine Output and Mortality in Patients Resuscitated from out of Hospital Cardiac Arrest Journal of Intensive Care Medicine
Variability in oxygen delivery with bag-valve-mask devices: An observational laboratory simulation study Anaesthesia and Intensive Care
Variation in Troponin I Measurement and the Cardiovascular Management Approach Following Elevated Troponin I Among Critically Ill Patients With Sepsis Critical Care Explorations
Ventilation during continuous compressions or at 30:2 compression-to-ventilation ratio results in similar arterial oxygen and carbon dioxide levels in an experimental model of prolonged cardiac arrest Intensive Care Medicine Experimental
Metadata
Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash