Emergency Evidence Updates – June 2024

Randomised Controlled Trials

Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: a stepped wedge cluster randomized clinical trial  Intensive Care Medicine

Head Injury Treatment With Healthy and Advanced Dietary Supplements: A Pilot Randomized Controlled Trial of the Tolerability, Safety, and Efficacy of Branched Chain Amino Acids in the Treatment of Concussion in Adolescents and Young Adults  Journal of Neurotrauma

Landiolol for refractory ventricular fibrillation in out-of-hospital cardiac arrest: A randomized, double-blind, placebo-controlled, pilot trial  Resuscitation

Noninvasive Ventilation for Preoxygenation during Emergency Intubation  NEJM

Online training to improve BLS performance with dispatcher assistance? Results of a cluster-randomised controlled simulation trial  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Out-of-Hospital Intranasal Ketamine as an Adjunct to Fentanyl for the Treatment of Acute Traumatic Pain: A Randomized Clinical Trial  Annals of Emergency Medicine

Reteplase versus Alteplase for Acute Ischemic Stroke  NEJM

Tenecteplase for Ischemic Stroke at 4.5 to 24 Hours without Thrombectomy  NEJM

 

Other Guidance/Reports

A Joint Trauma System Clinical Practice Guideline: Traumatic Brain Injury Management and Basic Neurosurgery in the Deployed Environment  Military Medicine

Antibiotic prophylaxis in injury: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document  Trauma Surgery & Acute Care Open

Frameworks Explainer for Children and Young People with Mental Health Concerns  PIER

Guidance for clinical practice using emergency and point-of-care ultrasonography  Acute Medicine & Surgery

Improving Outcomes After Post–Cardiac Arrest Brain Injury: A Scientific Statement From the International Liaison Committee on Resuscitation  Resuscitation

Spanish Society of Anesthesiology, Reanimation and Pain Therapy (SEDAR), Spanish Society of Emergency and Emergency Medicine (SEMES) and Spanish Society of Otolaryngology, Head and Neck Surgery (SEORL-CCC) Guideline for difficult airway management. Part I  Revista Española de Anestesiología y Reanimación (English Edition)

Spanish Society of Anesthesiology, Reanimation and Pain Therapy (SEDAR), Spanish Society of Emergency and Emergency Medicine (SEMES) and Spanish Society of Otolaryngology, Head and Neck Surgery (SEORL-CCC) Guideline for difficult airway management. Part II  Revista Española de Anestesiología y Reanimación (English Edition)

Rapid Acute Coronary Syndrome Evaluation Over One Hour With High-Sensitivity Cardiac Troponin I: A United States-Based Stepped-Wedge, Randomized Trial  Annals of Emergency Medicine

 

Primary Research

Prehospital

Analysis during chest compressions in out-of-hospital cardiac arrest patients, a cross/sectional study: The DEFI 2022 study Resuscitation

Association Between Emergency Medical Services Intervention Volume and Out-Of-Hospital Cardiac Arrest Survival: A Propensity Score Matching Analysis The Journal of Emergency Medicine

Evaluating the effectiveness of the maximum permitted dose of midazolam in seizure termination: Insights from New South Wales, Australia Emergency Medicine Australasia

Increased survival for resuscitated Utstein-comparator group patients conveyed directly to cardiac arrest centres in a large rural and suburban population in England  Resuscitation

Outcomes of adult patients discharged at scene by emergency medical services  Emergency Medicine Journal

Performance of 21 Early Warning System scores in predicting in-hospital deterioration among undifferentiated admitted patients managed by ambulance services  Emergency Medicine Journal

Successful prehospital ECMO in drowning resuscitation after prolonged submersion  Resuscitation Plus

The association of early naloxone use with outcomes in non-shockable out-of-hospital cardiac arrest  Resuscitation

 

General

Caregiver strain among relatives of out-of-hospital cardiac arrest survivors; The DANCAS relative survey  Resuscitation

Emergency Management and Nursing Considerations of Carotid Blowout Syndrome  Journal of Emergency Nursing

Health consumers’ ethical concerns towards artificial intelligence in Australian emergency departments  Emergency Medicine Australasia

Predicting severity of acute appendicitis with machine learning methods: a simple and promising approach for clinicians  BMC Emergency Medicine

Role identities of emergency medical services personnel and their associations with intention to leave the profession  BMC Emergency Medicine

Views of emergency care providers in providing healthcare for asylum seekers and refugees  Emergency Medicine Journal

 

Paediatric 

Evaluation of Automated Finger Compression for Capillary Refill Time Measurement in Pediatrics  Pediatric Emergency Care

Neck Point-of-Care Ultrasound for the Identification of Tongue-Base Cysts in Infants With Stridor A Case Series   Pediatric Emergency Care

Preprocedural Oxygenation and Procedural Oxygenation During Pediatric Procedural Sedation: Patterns of Use and Association With Interventions  Annals of Emergency Medicine

Presence of Microscopic Hematuria Does Not Predict Clinically Important Intra-Abdominal Injury in Children  Pediatric Emergency Care

Role of urine Gram stain in young febrile infants with a suspected urinary tract infection: a cohort study  Archives of Disease in Childhood

Routine Emergency Department Screening to Decrease Subsequent Physical Abuse  Annals of Emergency Medicine

Supplemental Oxygen for Pediatric Procedural Sedation: Common Sense Precaution or False Reassurance?  Annals of Emergency Medicine

Validation of the Hospital for Sick Children Algorithm for Discriminating Bacteremia From Contaminants in Children With a Preliminary Positive Blood Culture  Annals of Emergency Medicine

 

Adult

Anoxic Brain Injury: A Subtle and Often Overlooked Finding in Non-Fatal Intimate Partner Strangulation  The Journal of Emergency Medicine

Association between signs of life and survival in traumatic cardiac arrest patients: A nationwide, retrospective cohort study  Resuscitation Plus

Clinical decision aids and computed tomography coronary angiography in patients with suspected acute coronary syndrome  Emergency Medicine Journal

Comparing Intubation Rates in Patients Receiving Parenteral Olanzapine With and Without a Parenteral Benzodiazepine in the Emergency Department  Annals of Emergency Medicine

Development and validation of a community acquired sepsis-worsening score in the adult emergency department: a prospective cohort: the CASC score  BMC Emergency Medicine

Effects of mild hypercapnia on myocardial injury after out-of-hospital cardiac arrest. A sub-study of the TAME trial  Resuscitation

Factors Associated with Take Home Naloxone Refusal among Emergency Department Patients Participating in an Opioid Overdose Prevention Program  The Journal of Emergency Medicine

Incidence of intra-abdominal injuries in hemodynamically stable blunt trauma patients with a normal computed tomography scan admitted to the emergency department  BMC Emergency Medicine

Investigation of the Relationship Between the Measured Alpha Angle in Capnography and Readmission Within Thirty Days in COPD Who Presented to the Emergency Department  The Journal of Emergency Medicine

Low Incidence of Delayed Intracranial Hemorrhage in Geriatric Emergency Department Patients on Preinjury Anticoagulation Presenting with Blunt Head Trauma  The Journal of Emergency Medicine

Objective capillary refill to rapidly detect haemorrhage at the bedside  Emergency Medicine Journal

Patients suffering traumatic brain injury: patient characteristics, prehospital triage, primary referral and mortality – A population-based follow-up study  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Post-ROSC Atrial fibrillation is not associated with rearrest but is associated with stroke and mortality following out of hospital cardiac arrest  Resuscitation

Psychometric validation of a patient-reported experience measure for older adults attending the emergency department: the PREM-ED 65 study  Emergency Medicine Journal

Rapid Electroencephalography and Artificial Intelligence in the Detection and Management of Nonconvulsive Seizures  Annals of Emergency Medicine

Resuscitative Endovascular Balloon Occlusion of The Aorta (REBOA) And Mortality in Hemorrhagic Shock Associated with Severe Pelvic Fracture: a National Data Analysis  BMC Emergency Medicine

Safety of diltiazem for acute management of atrial fibrillation (AF) in patients with heart failure and reduced ejection fraction in the Emergency Department  The Journal of Emergency Medicine

The effect of circle of willis anatomy and scanning practices on outcomes for blunt cerebrovascular injuries  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

The link between carotid artery stenosis and outcomes in patients with refractory out-of-hospital cardiac arrest  Resuscitation

The Lipliner Sign: Potential Cause of a False Positive FAST Examination  The Journal of Emergency Medicine

Metadata

Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash