Emergency Evidence Updates – September 2022

Randomised Controlled Trials

Prehospital transdermal glyceryl trinitrate in patients with presumed acute stroke (MR ASAP): an ambulance-based, multicentre, randomised, open-label, blinded endpoint, phase 3 trial  The Lancet Neurology

Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis  NEJM


Self-harm: assessment, management and preventing recurrence NG225

Other Guidance/Reports

Acute Behavioural Disturbance in Emergency Departments (September 2022 update) – RCEM


Amniotic membrane transplantation for acute ocular burns

Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children

Nirmatrelvir combined with ritonavir for preventing and treating COVID‐19

Water for wound cleansing

Primary Research


Association of Prehospital Hypotension Depth and Dose with Survival Following Out-of-Hospital Cardiac Arrest  Resuscitation

Characteristics and comparison between e-scooters and bicycle-related trauma: a multicentre cross-sectional analysis of data from a road collision registry  BMC Emergency Medicine

Changes in health status and health related quality of life from six months to five years in out-of-hospital cardiac arrest survivors – A NORCAST sub study  Resuscitation

End-tidal carbon dioxide (ETCO2) at intubation and its increase after 10 minutes resuscitation predicts survival with good neurological outcome in out-of-hospital cardiac arrest patients  Resuscitation

Predefibrillation end-tidal CO2 and defibrillation success in out-of-hospital cardiac arrest: an observational cohort study  Journal of Emergency Medicine

The Association Between Arterial-End-Tidal Carbon Dioxide Difference and Outcomes After Out-of-Hospital Cardiac Arrest  Resuscitation

The effect of an on-site trauma surgeon during resuscitations of severely injured patients  BMC Emergency Medicine



A novel capnogram analysis to guide ventilation during cardiopulmonary resuscitation: clinical and experimental observations  Critical Care

A Single-Center Prospective Study of the Effects of Different Methods of Phlebotomy in the Emergency Department on Blood Sample Hemolysis Rates  Journal of Emergency Nursing

Case management intervention of high users of the emergency department of a Portuguese hospital: a before-after design analysis  BMC Emergency Medicine

Clean the skin: Reducing blood culture contamination in the emergency department  Emergency Medicine Australasia

Does wearing a surgical mask influence face touching by healthcare workers? A retrospective cohort study  Emergency Medicine Australasia

Establishing the research priorities of emergency medicine trainees, patients and carers across the UK and Ireland: the TERN Delphi study  Emergency Medicine Journal

Evaluating the utility of telehealth in emergency medicine  Emergency Medicine Australasia

Implementation and facilitation of post-resuscitation debriefing: a comparative crossover study of two post-resuscitation debriefing frameworks  BMC Emergency Medicine

Implementing a Resilience Bundle for Emergency Nurses: An Evidence-Based Practice Project  Journal of Emergency Nursing

Multi-disciplinary, simulation-based, standardised trauma team training within the Victorian State Trauma System  Emergency Medicine Australasia

Nurse, Provider, and Emergency Department Technician: Perceptions and Experiences of Violence and Aggression in the ED  Journal of Emergency Nursing

Quality Improvement: Implementing Nurse Standard Work in Emergency Department Fast-Track Area to Reduce Patient Length of Stay  Journal of Emergency Nursing

Realist analysis of whether emergency departments with primary care services generate ‘provider-induced demand’  BMC Emergency Medicine

The feasibility of a pediatric distance learning curriculum for emergency department nurses during the COVID-19 pandemic: An Improving Pediatric Acute Care Through Simulation (ImPACTS) collaboration  Journal of Emergency Nursing

Variation of in-hospital trauma team staffing: new resuscitation, new team  BMC Emergency Medicine



A Rare Complication of Anomalous Left Coronary Artery From the Pulmonary Artery Identified by Point-of-Care Ultrasound  Pediatric Emergency Care

Association of intensive care unit or paediatric intensive care unit admissions with the method of transporting patients: a multicentre retrospective study  BMC Emergency Medicine

Bandaids are not the fix: Examining the patterns of injury-related emergency department presentations in Australian children  Emergency Medicine Australasia

Comparison of Specialist and Nonspecialist Transport Teams for Emergency Neurosurgery  Pediatric Emergency Care

Diagnostic test accuracy of dipstick urinalysis for diagnosing urinary tract infection in febrile infants attending the emergency department  Archives of Disease in Childhood

Documented Visio-Vestibular Examination and Anticipatory Guidance for Pediatric Concussion Patients  Pediatric Emergency Care

Epidemiology of Pediatric Hand Injury at a Pediatric Department in Japan  Pediatric Emergency Care

Esophageal Bougienage for Management of Lodged Esophageal Coins – Safe, Effective, Efficient, and Underused  Pediatric Emergency Care

Evaluation of the Relationship Between Head Trauma and Attention-Deficit/Hyperactivity Disorder in Primary School Children Admitted to the Emergency Department  Pediatric Emergency Care

Factors Associated With Referral of Children With a Femur Fracture to a Social Worker by an Orthopedist for Suspected Child Abuse  Pediatric Emergency Care

Impact of different nebulisation systems on patient comfort in bronchiolitis: a randomised controlled cross-over trial  Archives of Disease in Childhood

Impact of Pediatric Dental Resident Availability in the Pediatric Emergency Department  Pediatric Emergency Care

Lateral flow test performance in children for SARS-CoV-2 using anterior nasal and buccal swabbing: sensitivity, specificity, negative and positive predictive values  Archives of Disease in Childhood

Pediatric Open Globe Injuries Caused by Firecrackers in a Tertiary Eye Care Hospital in Iran  Pediatric Emergency Care

Pharmacokinetics and tolerability of intranasal or intravenous administration of nalbuphine in infants  Archives of Disease in Childhood

Rate of invasive bacterial infection in recently vaccinated young infants with fever without source  Archives of Disease in Childhood

Telescoping the Diagnostic Process  NEJM



Considering guardsman fracture as a differential in mandibular injuries  Trauma

Cryoprecipitate transfusion in trauma patients attenuates hyperfibrinolysis and restores normal clot structure and stability: Results from a laboratory sub-study of the FEISTY trial  Critical Care

Differences in characteristics between patients ≥ 65 and < 65 years of age with orthopaedic injuries after severe trauma  Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Early identification of bleeding in trauma patients: external validation of traumatic bleeding scores in the Swiss Trauma Registry  Critical Care

Raising the D-dimer threshold for ruling out pulmonary embolism: A single-site, observational study with a historical comparison  Emergency Medicine Australasia

Refractory Anaphylactic Shock Requiring Emergent Venoarterial Extracorporeal Membrane Oxygenation in the Emergency Department: A Case Report  Journal of Emergency Nursing

The Man Who Mistook a Hat for His Wife: Case Report of Aortic Dissection Presenting with Acute Hyperfamiliarity for Faces  Annals of Emergency Medicine



Summary author: Rebecca Howes @ClinicalLibsPHU
Summary date:
Picture by: Ehimetalor Akhere Unuabona on Unsplash

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