Category: Uncategorized

Sodium Bicarbonate for Metabolic Acidosis in the Intensive Care Unit (SODa-BIC) trial

29 June 2026 Aniket Nadkarni Intensive Care Medicine, Uncategorized Leave a comment

Sodium Bicarbonate for Metabolic Acidosis in the Intensive Care Unit (SODa-BIC) trial The SODa-BIC Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. NEJM 2026; doi: 10.1056/NEJMoa2600526 Clinical Question In critically ill adults with metabolic acidosis (pH < 7.30) receiving vasopressors, does sodium bicarbonate decrease the risk of major adverse kidney events within 30 days compared […]

PREPARE II

13 January 2023 Omar Jundi Evidence-based Medicine, Intensive Care Medicine, Uncategorized Leave a comment

Effect of Fluid Bolus Administration on Cardiovascular Collapse Among Critically Ill Patients Undergoing Tracheal Intubation @DerekRussellMD. JAMA; 328(3):270-279. doi:10.1001/jama.2022.9792 Clinical Question In critically ill adult patients undergoing tracheal intubation and positive pressure ventilation, does intravenous infusion of a 500ml fluid bolus vs no fluid bolus, decrease the incidence of cardiovascular collapse during, or shortly after the procedure? Background Tracheal intubation […]