REDUCE
Is short-term (5 days) systemic glucocorticoid treatment in patients with COPD exacerbation as good as conventional (14 days) treatment in clinical outcome and does it decrease the overall exposure to steroids?
Continue reading »Category: Emergency Medicine
A collection of TBL summaries relevant to Emergency Medicine
VSE
In patients in cardiac arrest, does vasopressin + epinephrine during CPR combined with steroid supplementation during and after CPR, improve survival to discharge with a good neurological outcome, in comparison to the use of epinephrine alone?
Continue reading »Ferrer
In patients with severe sepsis or septic shock, is the timing of first administration of antibiotics associated with the in-hospital mortality rate?
Continue reading »Kumar
Does a delay in antibiotic administration in patients with septic shock result in an increased mortality?
Continue reading »3Mg trial
Does intravenous or nebulised MgSO4 improve symptoms of breathlessness and reduce the need for hospital admission in adults with severe acute asthma?
Continue reading »Chatterjee
In patients with PE, does the addition of thrombolysis to anticoagulation, compared with anticoagulation alone, affect mortality and bleeding complications?
Continue reading »TOPCOAT
In patients with submassive PE, does the use of tenecteplase + heparin, compared to heparin alone, improve patient orientated outcomes?
Continue reading »PEITHO
In patients with intermediate-risk/sub-massive pulmonary embolism (PE), does the addition of tenecteplase, compared with heparin alone improve the composite outcome of death and haemodynamic decompensation?
Continue reading »MOPETT
In patients with moderate Pulmonary Embolism (PE), does low dose thrombolysis + anticoagulation, compared with anticoagulation alone, reduce pulmonary artery pressure at 28 months?
Continue reading »MAPPETT 3
In patients with sub-massive PE, does the use of thrombolysis + heparin, compared to heparin alone, reduce the composite outcome of mortality or clinical deterioration?
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