A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
In patients in cardiac arrest, does vasopressin + epinephrine during CPR combined with steroid supplementation during and after CPR, improve survival to discharge with a good neurological outcome, in comparison to the use of epinephrine alone?
Continue reading »In mechanically ventilated adult patients with a high risk of prolonged ventilation, does early tracheostomy compared with late tracheostomy reduce mortality at 30 days?
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Does early tracheostomy reduce duration of mechanical ventilation and mortality in comparison with prolonged intubation in patients with head injury?
Continue reading »In patients with severe sepsis or septic shock, is the timing of first administration of antibiotics associated with the in-hospital mortality rate?
Continue reading »Does a delay in antibiotic administration in patients with septic shock result in an increased mortality?
Continue reading »Does intravenous or nebulised MgSO4 improve symptoms of breathlessness and reduce the need for hospital admission in adults with severe acute asthma?
Continue reading »In adult patients undergoing mechanical ventilation, does a strategy involving no continuous sedation, compared to a strategy of continuous sedation by infusion with a daily interruption, reduce the number of days of mechanical ventilation in the first 4 weeks?
Continue reading »In patients with septic shock, is mortality affected by the use of adrenaline (epinephrine) alone in comparison to noradrenaline ± dobutamine?
Continue reading »Is extracorporeal membrane oxygenation (ECMO) a safe, efficacious and cost-effective treatment compared with conventional ventilation for the management of severe adult respiratory failure?
Continue reading »In patients with PE, does the addition of thrombolysis to anticoagulation, compared with anticoagulation alone, affect mortality and bleeding complications?
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