ARISE
In adult patients with septic shock, does early goal-directed therapy (EGDT) compared with standard therapy reduce mortality at 90 days?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A category to collect all the summaries, so that they can be used in menus and widgets. Please don’t expand this – “Specialties” and “Special Topics” have been created as a custom category sets for the clinical topics.
In adult patients with septic shock, does early goal-directed therapy (EGDT) compared with standard therapy reduce mortality at 90 days?
Continue reading »In adults with severe sepsis or septic shock, does the use of early goal-directed therapy (EGDT) reduce the mortality?
Continue reading »Does chlorhexidine-impregnated dressing compared to conventional site care prevent catheter-related blood stream infections and catheter colonisation?
Continue reading »In patients renal dysfunction, does dopamine reduce the severity of acute kidney injury?
Continue reading »In critically ill patients with relative contraindications to early enteral nutrition (EN), does providing early parenteral nutrition (PN), improve mortality?
Continue reading »Does the use of Selective Decontamination of the Digestive Tract (SDD) affect ICU and hospital mortality and the acquisition of resistant organisms?
Continue reading »In critically ill patients does early treatment with haloperidol decrease the time that survivors spend in delirium or coma?
Continue reading »Pulmonary Artery Catheters in patient Management PAC-MAN study group, Lancet 2005;366;472-477 Clinical Question In critically ill patients, does the use of a pulmonary artery catheter (PAC) reduce mortality? Design Randomised controlled trial Non-blinded Stratified by age and presumptive clinical syndrome Intention to treat analysis Power calculation: 1281 patients would allow detection of a 10% change in absolute hospital mortality, with […]
Continue reading »In adults with a head injury, do early corticosteroids compared to placebo reduce death and disability?
Continue reading »Does a prolonged course of intravenous methylprednisolone improve lung function and reduce mortality in patients with unresolving ARDS
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