Tag: Delirium

Delirium Reduction via Scripted Family Voice Recordings in Critically Ill Patients Receiving Mechanical Ventilation

28 January 2026 Mark Giza Intensive Care Medicine, Summaries Leave a comment

Delirium Reduction via Scripted Family Voice Recordings in Critically Ill Patients Receiving Mechanical Ventilation CL Munro. Am J Crit Care. 2025; Nov 1;34(6):429-437. doi: 10.4037/ajcc2025486 Clinical Question In mechanically ventilated adult ICU patients, does a structured voice reorientation intervention recorded by family members, compared to usual care, reduce delirium? Background Delirium affects a significant proportion of patients receiving mechanical ventilation. […]

Quetiapine Versus Haloperidol for Delirium

22 November 2024 Hrishee Vaidya Intensive Care Medicine, Summaries Leave a comment

Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium: Randomized Controlled Trial Zakhary et al. Neurocritical Care; Oct;41(2):550-557. doi:10.1007/s12028-024-01948-w Clinical Question In critically ill patients with delirium, does quetiapine in comparison to haloperidol, reduce the severity of delirium? Background Delirium affects 30-50% of adult ICU patients Haloperidol is licensed for the treatment of acute delirium in the UK Previous RCTs […]

AID-ICU

21 April 2023 David Slessor Intensive Care Medicine, Summaries Leave a comment

In patients in the ICU with delirium, does haloperidol compared with placebo, increase the number of days alive and out of the hospital at 90 days?

Pro-MEDIC

19 December 2022 George Walker Intensive Care Medicine Leave a comment

In adults with an expected ICU stay of > 72 hours, does the provision of enteral melatonin compared to placebo increase the number of delirium-free assessments within 14 days or before ICU discharge?

REDUCE Haloperidol

21 June 2019 Duncan Chambler Intensive Care Medicine Leave a comment

In critically ill adults, does haloperidol 1 mg or haloperidol 2 mg given three times a day compared to placebo reduce mortality?

SPICE III

24 May 2019 Celia Bradford Intensive Care Medicine 3 comments

In ventilated, critically ill patients, does the use of dexmedetomidine as the primary sedative agent compared with usual sedative agents effect 90 day mortality?

MIND-USA

16 November 2018 Fraser Magee Intensive Care Medicine Leave a comment

In delirious adult ICU patients, does the administration of haloperidol or ziprasidone reduce the duration of delirium when compared with placebo?

Nishikimi

13 April 2018 Duncan Chambler Intensive Care Medicine Leave a comment

In critically ill adults, does the administration of ramelteon compared to placebo reduce the length of intensive care stay?

Skrobik

23 March 2018 Imelda Galvin Intensive Care Medicine 4 comments

In delirium free critically ill adult patients receiving sedation, does the addition of nocturnal low dose dexmedetomidine prevent delirium and improve sleep?

MoDUS

8 December 2017 Duncan Chambler Intensive Care Medicine One comment

In mechanically ventilated patients, does the early administration of simvastatin compared to placebo reduce the incidence of brain dysfunction (delirium and / or coma)?

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