Hernandez 2
In critically ill patients who are at high risk for re-intubation, is high flow nasal oxygen non-inferior to non-invasive ventilation in reducing re-intubation and post-extubation respiratory failure?
Continue reading »Tag: Featured
Kentish-Barnes
Among relatives who died in the Intensive Care Unit (ICU), does a condolence letter from a clinician, compared to no condolence letter, effect grief symptoms?
Continue reading »PRECISE
In patients with moderate-to-severe sciatica, does pregabalin compared to placebo reduce leg pain?
Continue reading »REVIVE
In patients that survive critical illness, does a post-discharge exercise programme compared to standard post-discharge care improve physical function?
Continue reading »Detsky
What is the discriminative accuracy of physicians and nurses in predicting 6-month mortality and functional outcomes of critically ill patients?
Continue reading »TRICOP
In cancer patients with septic shock does a restrictive vs. a liberal transfusion threshold reduce 28 day mortality?
Continue reading »ATHOS-3
In patients with refractory vasodilatory shock does the addition of angiotensin II improve blood pressure compared with standard vasopressor therapy?
Continue reading »Critical Appraisal – Glossary
Rather than reinvent the wheel, we are delighted to include a link to the RCEM Critical Appraisal Dictionary. The RCEM learning site provides excellent open access educational resources, including critical care appraisal modules
Continue reading »INSTINCT
In patients with necrotising soft tissue infection (NSTI), does the use of intravenous immunoglobulin (IVIG) compared to placebo improve patient reported physical outcomes?
Continue reading »Type 1 and 2 Errors
In statistical hypothesis testing, a type I error is the incorrect rejection of a true null hypothesis (a “false positive”), while a type II error is incorrectly retaining a false null hypothesis (a “false negative”). The more you try and avoid a Type I error (false positive), the more likely a Type II error (false negative) may happen. Researchers have found that an alpha level of 5% is a good balance between these two issues
Continue reading »