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In patients with coma following cardiac arrest with a non-shockable rhythm, does moderate hypothermia vs. normothermia, improve neurological outcome?
Continue reading »A compendium of critical appraisals in Intensive Care Medicine research and related specialties
A collection of TBL summaries relevant to Emergency Medicine
In patients with coma following cardiac arrest with a non-shockable rhythm, does moderate hypothermia vs. normothermia, improve neurological outcome?
Continue reading »In trauma patients with hemorrhagic shock, does the use of low-dose arginine vasopressin compared to placebo reduce the volume of blood products transfused?
Continue reading »Transfusion Volume for Children with Severe Anaemia in Africa K.Maitland. New England Journal of Medicine August 1st 2019; 381:5; 420-431. doi: 10.1056/NEJMoa1900100 Clinical Question In African children presenting to hospital with severe anaemia, is a blood transfusion volume of 30 ml/kg superior to 20 ml/kg in reducing 28 day mortality? Background Severe anaemia is a major cause of death and […]
Continue reading »In children hospitalised with uncomplicated severe anaemia, is an immediate blood transfusion strategy superior to delayed transfusion in reducing 28-day mortality?
Continue reading »In severely injured trauma patients, where anticoagulation is contraindicated, does the use of prophylactic inferior vena cava filters reduce the incidence of pulmonary embolism (PE)?
Continue reading »In patients with intermediate risk PE, do low doses of tPA and short durations of ultrasound facilitated catheter directed thrombolysis, result in a reduction in RV:LV diameter at 48 hours?
Continue reading »In adult patients with sepsis-associated coagulopathy does the administration of human recombinant thrombomodulin (rhsTM) compared to placebo reduce 28 day mortality?
Continue reading »In patients with acute ischaemic stroke, with salvageable brain tissue, does alteplase compared with placebo, administered between 4.5 – 9 hours post stroke onset, improve functional outcome at 90 days?
Continue reading »In adult ICU patients undergoing tracheal intubation, does bag mask ventilation (BMV) between induction and laryngoscopy reduce the risk of hypoxaemia?
Continue reading »In patients presenting to the Emergency Department (ED) in cardiac arrest, does a standardised point-of-care ultrasound protocol, compared with usual care, affect the length of resuscitation, frequency of interventions, and clinical outcomes?
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